2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N9782
    2,7-Dihydroxy-1,6-dimethylpyrene 468103-76-6 98%
    2,7-Dihydroxy-1,6-dimethylpyrene is a pyrene that can be isolated from the wetland plant Juncus acutus and inhibits growth of the freshwater green alga Selenastrum capricornutum.
    2,7-Dihydroxy-1,6-dimethylpyrene
  • HY-N9837
    Methyl lucidenate L 110267-46-4 98%
    Methyl lucidenate L is a natural triterpene acid methyl ester with inhibitory effects on EBV (Epstein-Barr virus) activation.
    Methyl lucidenate L
  • HY-N9923
    2-C-Methyl-D-erythritol 4-phosphate 206440-72-4 98%
    2-C-Methyl-D-erythritol 4-phosphate is a metabolite intermediate exclusive to the non-mevalonate MEP pathway, predominantly found in prokaryotes, serving as a precursor for the synthesis of isoprenoids and non-isoprenoids, including vitamins; its absence in humans makes it a promising target for the development of bacterium-specific drugs aimed at treating infectious diseases.
    2-C-Methyl-D-erythritol 4-phosphate
  • HY-N9947
    Methyl-6-gingerol 23513-10-2 98%
    Methyl-6-gingerol is an antimicrobial agent derived from Aframomum melegueta that exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species.
    Methyl-6-gingerol
  • HY-P1612
    Hormaomycin 121548-21-8 98%
    Hormaomycin is a potent and selective macrocyc antibiotic agent. Hormaomycin has broad-spectrum antibiotic activity against numerous Gram-positive.
    Hormaomycin
  • HY-P1638
    Isariin A 10409-85-5 98%
    Isariin A is a cyclodepsipeptide isolated from the fungus Isaria cretacea, which exhibits antimalarial activity.
    Isariin A
  • HY-P1674
    Murepavadin 944252-63-5 98%
    Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance.
    Murepavadin
  • HY-P1704
    Cyclosporin E 63798-73-2 98%
    Cyclosporin E (11-Demethylcyclosporin A) is a cyclic oligopeptide that can be isolated from fungi such as TTrichoderma polysporum and other imperfect fungi. Cyclosporin E belongs to the Cyclosporins family. Cyclosporin E can be used for studying the structure-activity relationships and molecular dynamic properties of cyclosporin compounds. As a structural control compound, Cyclosporin E holds significant research value in the fields of medicinal chemistry and biophysics.
    Cyclosporin E
  • HY-P1708
    Enopeptin A 139601-96-0 98%
    Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC=25 μg/mL), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs=200 μg/mL); however, it is not inhibitory to fungi.
    Enopeptin A
  • HY-P1937
    Cyclo(-Met-Pro) 53049-06-2 98%
    Cyclo(-Met-Pro) is a cyclic dipeptide consisting of the amino acids methionine and proline. Cyclo(-Met-Pro) exhibits weak inhibitory activity against the influenza A virus (H3N2) (5 mM, 2.1% inhibition), while cis-cyclo(Leu-Pro) and cis-cyclo(Phe-Pro) shows significant antiviral activity.
    Cyclo(-Met-Pro)
  • HY-P1957
    Dihydrocyclosporin A 59865-15-5 98%
    Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic.
    Dihydrocyclosporin A
  • HY-P1991
    Isariin D 80111-97-3 98%
    Isariin D is a cyclodepsipeptide isolated from the fungus Isaria felina, which exhibits significant insecticidal activity against Galleria mellonella larvae.
    Isariin D
  • HY-P1992
    Isariin B 80111-95-1 98%
    Isariin B is a cyclodepsipeptide isolated from the fungus Isaria felina, which exhibits antimalarial activity.
    Isariin B
  • HY-P2032
    Cyclochlorotine 12663-46-6 98%
    Cyclochlorotine is a mycotoxin that can be extracted from the yellow rice infectant Penicillium islandicum Sopp. Cyclochlorotine promotes glycogenolysis, inhibits glycogen synthesis, affects fat synthesis and protein synthesis in liver cells. Cyclochlorotine exhibits chronic toxicity in liver that induces liver fibrosis and cirrhosis in mouse models. Cyclochlorotine exhibits carcinogenicity.
    Cyclochlorotine
  • HY-P2209
    Nummularine B 53947-96-9 98%
    Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis.
    Nummularine B
  • HY-P2783
    Destruxin B2 79386-00-8 98%
    Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC50 1.30 μM.
    Destruxin B2
  • HY-P3178
    Pyrimidine nucleoside phosphorylase 9055-35-0 98%
    Pyrimidine nucleoside phosphorylase is an enzyme. The Pyrimidine nucleoside phosphorylase in Mycoplasma hyorhinis efficiently catalyzes the phosphorylation of thymidine and uridine, and exhibits (2,-deoxy)ribosyltransferase activity.
    Pyrimidine nucleoside phosphorylase
  • HY-P5407
    HD5 798569-33-2 98%
    HD5 is an innate immune effector peptide and SARS-CoV Inhibitor. HD5 binds to the ligand-binding domain of angiotensin-converting enzyme-2 (ACE2) via multiple hydrogen bonds to competitively block the receptor, shielding it from viral recognition. HD5 can be used for the research of COVID-19, HPV16 infection, epithelial ovarian cancer, small-cell lung cancer, and colon cancer.
    HD5
  • HY-P5546
    Lynronne-2 98%
    Lynronne-2 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 32-256 μg/mL for methicillin-resistant MRSA strains). Lynronne-2 is also effective against P. aeruginosa infection
    Lynronne-2
  • HY-P5550
    Urumin 2215863-74-2 98%
    Urumin has antiviral activity against the human influenza A virus. Urumin inhibits the growth of PR8 influenza virus (IC50: 3.8 μM). Urumin targets the conserved stalk of H1 hemagglutini, and is effective at neutralizing drug-resistant H1 influenza viruses. Urumin protects naive mice from lethal influenza infection.
    Urumin
Cat. No. Product Name / Synonyms Application Reactivity