2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N11761
    4,5-Dihydropiperlonguminine 23512-53-0 98%
    4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars.
    4,5-Dihydropiperlonguminine
  • HY-N11778
    Bequinostatin C 152175-74-1 98%
    Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50=40 μg/mL for human GSTP1).
    Bequinostatin C
  • HY-N1181R
    Tamarixetin (Standard) 603-61-2
    Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways.
    Tamarixetin (Standard)
  • HY-N11857
    Gentamicin C2 25876-11-3 98%
    Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections.
    Gentamicin C2
  • HY-N11920
    Kadsurenin B 145701-13-9 98%
    Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc.
    Kadsurenin B
  • HY-N12017
    3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester 128717-92-0 98%
    3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester is a hederagenin-type saponin with antitumor and anti-inflammatory properties.
    3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester
  • HY-N12056
    Cyclo(L-leucyl-L-valyl) 15136-24-0 99.35%
    Cyclo(L-leucyl-L-valyl) inhibits Aflatoxin production by Aspergillus parasiticus.Cyclo(L-leucyl-L-valyl) inhibits transcription of the Aflatoxin-related genes aflR, hexB, pksL1, and dmtA..
    Cyclo(L-leucyl-L-valyl)
  • HY-N12076
    11-Deoxydoxorubicin 71800-89-0 98%
    11-Deoxydoxorubicin has anti-Gram-positive bacteria, negative bacteria and tumor activity.
    11-Deoxydoxorubicin
  • HY-N12082
    HIV-IN-8 130286-75-8 98%
    HIV-IN-8 (Compound 9) is a HIV inhibitor. HIV-IN-8 inhibits HIV replication with an EC50 of 13 μg/mL.
    HIV-IN-8
  • HY-N12097
    Qianhucoumarin D 20516-19-2 98%
    Qianhucoumarin D, pyranocoumarin, is a nature product. Qianhucoumarin D can be isolated from the roots of Peucedanum praeruptorum. Qianhucoumarin D can be used for the research of inflammation and cancer.
    Qianhucoumarin D
  • HY-N12105
    Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside 1015175-06-0 98%
    Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside is an anti-hepatitis B virus (anti-HBV) agent. Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside inhibits HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) secretion on Hep G2.2.15 cell line, with IC50 values of 1.67 and >2.15 mM, respectively.
    Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside
  • HY-N12118
    Piperanine 23512-46-1 98%
    Piperanine is an antifungal agent. Piperanine shows growth inhibition against the fungus Cladosporium claspoirioides. Piperanine can be isolated from the fruits of Piper retrofractum.
    Piperanine
  • HY-N12149
    Axinysone B 1114491-60-9 98%
    Axinysone B can be isolated from Laurencia similis. Axinysone B has antibacterial activity against Staphylococcus sp..
    Axinysone B
  • HY-N12151
    Chaparrinone 22611-34-3 98%
    Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively).
    Chaparrinone
  • HY-N12164
    Linearmycin B 182291-65-2 98%
    Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively.
    Linearmycin B
  • HY-N12171
    Isoreserpiline 572-67-8 98%
    Isoreserpiline is an orally active and BBB-penetrable indole alkaloids with antibacterial and antipsychotic activity. Isoreserpiline is even more effective when used in combination with antibiotics and inhibits the activity of bacterial efflux pumps. Isoreserpiline improves Amphetamine-induced hyperactivity in mice .
    Isoreserpiline
  • HY-N12178
    16-Deethylindanomycin 106803-22-9 98%
    16-Deethylindanomycin (A 83094A) is an antibiotic, which can be produced by Streptomyces setonii. 16-Deethylindanomycin exhibits antimicrobial activities against gram-positive bacteria Staphylococcus spp. and Streptococcus with MIC of 2-4 µg/mL. 16-Deethylindanomycin exhibits anticoccidial activity against Eimeria tenella.
    16-Deethylindanomycin
  • HY-N12180
    Hodgkinsine B 586955-76-2 98%
    Hodgkinsine B is an opioid receptor agonist and NMDA receptor antagonist, which has analgesic and anti-injurial effects. In addition, Hodgkinsine B has antiviral, antibacterial and antifungal activities.
    Hodgkinsine B
  • HY-N12223
    Piericidin B 16891-54-6 98%
    Piericidin B (compound 8) is an antibiotic that provides strong antibacterial defense for wasp larvae.
    Piericidin B
  • HY-N12232
    Carbazomycin D 108073-63-8 98%
    Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively.
    Carbazomycin D
Cat. No. Product Name / Synonyms Application Reactivity