2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N15600
    Merulidial 68053-32-7 98%
    Merulidial (Compound 1) is an antibiotic and cytotoxic agent with a sesquiterpene dialdehyde structure. Merulidial significantly inhibits the germination of spores and the hyphal growth of the wood-roting basidiomycete Heterobasidion annosum (H. annosum) and the saprophytic mould Cladosporium cucumerinum (C.cucumerinum). Merulidial also inhibits a variety of bacteria, algae and DNA synthesis of ECA cells. Merulidial shows a strong anticancer activity with IC50 s of 20 and 10 μg/mL for ECA and L1210 cells, respectively .
    Merulidial
  • HY-N1581R
    Quassin (Standard) 76-78-8
    Quassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
    Quassin (Standard)
  • HY-N16389
    Oresbiusin A 457893-80-0 98%
    Oresbiusin A (Compound 6) is a plant secondary metabolite. Oresbiusin A can be isolated from Origanum dictamnus L. Oresbiusin A has antimicrobial activity against Gram-negative bacterium, such as Acinetobacter hemolyticus, Empedobacter brevis and Pseudomonas aeruginosa with a MIC of 0.236 μg/mL for Acinetobacter hemolyticus.
    Oresbiusin A
  • HY-N16403
    Aspergillusidone F 1558007-47-8 98%
    Aspergillusidone F is a Depsidone and antibacterial agent. Aspergillusidone F can be isolated from a marine fungus Aspergillus unguis. Aspergillusidone F potently inhibits Aromatase with an IC50 of 0.5 μM. Aspergillusidone F exhibits antibacterial activity against Pseudomonas aeruginosa and Methicillin (HY-121544)-resistant Staphylococcus aureus. Aspergillusidone F exhibits potent larvicidal activity against Artemia salina larvae, with an LC50 value of 12.8 μM. Aspergillusidone F exhibits anticancer activity against intrahepatic cholangiocarcinoma, non-small cell lung cancer, and acute lymphoblastic leukemia.
    Aspergillusidone F
  • HY-N16435
    Plumericin 77-16-7 98%
    Plumericin is an anti-inflammatory, antioxidant, and antibacterial agent. Plumericin reduces Apoptosis, promotes Nrf-2 and inhibits NF-κB and AhR activation, blocks STAT3 signaling. Plumericin inhibits Mycobacterium tuberculosis growth. Plumericin can be used for the research of chronic kidney disease, vascular diseases, inflammatory bowel diseases, peritonitis, and tuberculosis.
    Plumericin
  • HY-N16455
    (S)-2-Hydroxy-3-decanone 383416-53-3 98%
    (S)-2-Hydroxy-3-decanone is the primary sex pheromone component of Xylotrechus quadripes beetles, functioning as a volatile olfactory agonist. (S)-2-Hydroxy-3-decanone is promising for research of pests and diseases.
    (S)-2-Hydroxy-3-decanone
  • HY-N16456
    3-Hydroxy-2-decanone 68113-61-1
    3-Hydroxy-2-decanone is a minor component of sex pheromone in Xylotrechus quadripes beetles. 3-Hydroxy-2-decanone is promising for research of pests and diseases.
    3-Hydroxy-2-decanone
  • HY-N16462
    2-(2-Heptenyl)-3-methyl-4(1H)-quinolone 124201-44-1
    2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is a quinoline alkaloid found in Burkholderia sp. VY81. 2-(2-Heptenyl)-3-methyl-4(1H)-quinolone is promising for research of bacterial diseases in rice (e.g., soft rot) and other plant pathogens (e.g., Pythium ultimum, Fusarium oxysporum).
    2-(2-Heptenyl)-3-methyl-4(1H)-quinolone
  • HY-N16491
    Agrimol C 55785-59-6
    Agrimol C is a phloroglucino found in Chinese drugs Xian he cao. Agrimol C shows antimicrobial activity against Staphlococcus aureus with MIC with 50 μg/mL. Agrimol C can be used for the research of infection.
    Agrimol C
  • HY-N16497
    Leptosperin 1431845-42-9 98%
    Leptosperin is a glycoside of methyl syringate found in manuka honey derived from the Leptospermum species Leptospermum scoparium. Leptosperin exhibits antibacterial activity. Leptosperin can be used for the research of infection.
    Leptosperin
  • HY-N16657
    Fusaricidin B 189757-88-8 98%
    Fusaricidin B (LI-F 04b) is one of the components of a lipopeptide biosurfactant extracted from the marine bacterium Paenibacillus polymyxa. Fusaricidin B can significantly inhibit the formation of multiple single species biofilms, including Gram positive and Gram negative bacteria. Fusaricidin B also has inhibitory effects on complex biofilms and can effectively destroy mature biofilms that have already formed. Fusaricidin B can be used for research on bacterial infections.
    Fusaricidin B
  • HY-N16672
    SMTP-0 951393-54-7
    SMTP-0 (ent-Stachybotrin B) is an enantiomer of Stachybotrin B isolated from Stachybotrys microspora. SMTP-0 is the simple homologues of the SMTP nonlysine-analog plasminogen modulator family but shows no plasminogen modulator activity. SMTP-0 exhibits antibacterial and antifungal effects. SMTP-0 can be used for the research of infection.
    SMTP-0
  • HY-N1667R
    2',4'-Dihydroxy-6'-Methoxyacetophenone (Standard) 3602-54-8 98%
    2',4'-Dihydroxy-6'-Methoxyacetophenone is a phenolic acetophenone from Artemisia annua. Artemisia annua is an analog of Artemisinin that is effective in the research of malaria.
    2',4'-Dihydroxy-6'-Methoxyacetophenone (Standard)
  • HY-N1677R
    2,6-Dimethoxy-1,4-benzoquinone (Standard) 530-55-2 98%
    2,6-Dimethoxy-1,4-benzoquinone (Standard) is the analytical standard of 2,6-Dimethoxy-1,4-benzoquinone (HY-N1677). This product is intended for research and analytical applications. 2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness.
    2,6-Dimethoxy-1,4-benzoquinone (Standard)
  • HY-N17258
    Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) 129235-39-8 98%
    Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) is an oviposition inhibitory factor. Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) can be isolated from the leaves of Orixa japonica. When presented together with the oviposition stimulant from Citrus unshiu (Satsuma mandarin), Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside) inhibits oviposition by gravid female Papilio xuthus (Asian swallowtail).
    Quercetin 3-O-(2G-β-D-xylopyranosylrutinoside)
  • HY-N17267
    2-Deoxy-20-hydroxyecdysone 17942-08-4
    2-Deoxy-20-hydroxyecdysone is an ecdysteroid. 2-Deoxy-20-hydroxyecdyson can be isolated from zoanthid Zoanthus sp.. 2-Deoxy-20-hydroxyecdysone exhibits lower moulting hormone activity than 20-hydroxyecdysone in Musca bioassays.
    2-Deoxy-20-hydroxyecdysone
  • HY-N17348
    5,6,7,8-Tetramethoxyflavone 3162-43-4
    5,6,7,8-Tetramethoxyflavone is a flavonoid with antifungal and antibacterial activities, capable of inhibiting the growth of *Staphylococcus aureus* and *Candida albicans*. 5,6,7,8-Tetramethoxyflavone can be utilized in research related to infections [1].
    5,6,7,8-Tetramethoxyflavone
  • HY-N1739R
    Tectoquinone (Standard) 84-54-8 98%
    Tectoquinone (Standard) is the analytical standard of Tectoquinone. This product is intended for research and analytical applications. Tectoquinone (2-Methylanthraquinone) is an inhibitor for SARS CoV-2 major protease (SARS CoV-2 Mpro). Tectoquinone exhibits anti-termite and antiviral activities.
    Tectoquinone (Standard)
  • HY-N18435
    Komaroidine 6649-76-9 98%
    Komaroidine is a bactericidal agent. Komaroidine induces reactive oxygen species (ROS) bursts in bacterial cells, disrupts antioxidant enzyme function and redox homeostasis, increases membrane permeability, and triggers bacterial apoptosis. Komaroidine suppresses bacterial burden within infected plant tissues.Komaroidine exhibits broad-spectrum antibacterial activity against phytopathogenic bacteria including Xanthomonas oryzae pv. oryzae, Xanthomonas axonopodis pv. citri, and Pseudomonas syringae pv. actinidiae. Komaroidine can be used for the research of rice bacterial leaf blight.
    Komaroidine
  • HY-N18500
    (+)-Adlumidine 550-49-2 98%
    (+)-Adlumidine (Adlumidine) is an isoquinoline alkaloid. (+)-Adlumidine efficiently binds to two key targets of SARS-CoV-2, Mpro and RBD, with IC50 values of 953.86 nM and 9.48 μM, respectively. (+)-Adlumidine exerts significant positive inotropic effects and certain positive chronotropic effects on cultured mouse embryonic cardiomyocytes. (+)-Adlumidine can be used for research on cardiovascular-related diseases and SARS-CoV-2 infection.
    (+)-Adlumidine
Cat. No. Product Name / Synonyms Application Reactivity