2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-101444AR
    PAβN dihydrochloride (Standard) 100929-99-5 98%
    PAβN (dihydrochloride) (Standard) is the analytical standard of PAβN (dihydrochloride) (HY-101444A). This product is intended for research and analytical applications. PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
    PAβN dihydrochloride (Standard)
  • HY-101634AR
    ABT-072 potassium trihydrate (Standard) 1132940-31-8 98%
    ABT-072 (potassium trihydrate) (Standard) is the analytical standard of ABT-072 (potassium trihydrate) (HY-101634A). This product is intended for research and analytical applications. ABT-072 (potassium trihydrate) is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM).
    ABT-072 potassium trihydrate (Standard)
  • HY-101954AR
    Inarigivir ammonium (Standard) 2172788-92-8 98%
    Inarigivir ammonium (Standard) is the analytical standard of Inarigivir ammonium (HY-101954A). This product is intended for research and analytical applications. Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) ammonium acts as a RIG-I (Retinoic acid-inducible gene-I) agonist to activate cellular innate immune responses.
    Inarigivir ammonium (Standard)
  • HY-103017AR
    JH-X-119-01 (Standard) 2227368-54-7
    JH-X-119-01 (Standard) is the analytical standard of JH-X-119-01 (HY-103017A). This product is intended for research and analytical applications. JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM.
    JH-X-119-01 (Standard)
  • HY-103160AR
    EHNA hydrochloride (Standard) 58337-38-5
    EHNA hydrochloride (Standard) is the analytical standard of EHNA hydrochloride (HY-103160A). This product is intended for research and analytical applications. EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects.
    EHNA hydrochloride (Standard)
  • HY-103397AR
    Dihydrokalafungin (Standard) 98392-26-8 98%
    Dihydrokalafungin (Standard) is the analytical standard of Dihydrokalafungin (HY-103397A). This product is intended for research and analytical applications. Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system.
    Dihydrokalafungin (Standard)
  • HY-10353AS2
    Raltegravir-d4 potassium 98%
    Raltegravir-d4 (potassium) (MK 0518-d4 (potassium)) is deuterium labeled Raltegravir (potassium). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
    Raltegravir-d4 potassium
  • HY-103639AR
    M62812 (Standard) 613263-00-6
    M62812 (Standard) is the analytical standard of M62812 (HY-103639A). This product is intended for research and analytical applications. M62812 is a toll-like receptor 4 (TLR4) signaling inhibitor. M62812 inhibits endothelial and leukocyte activation and prevents lethal septic shock in mice. M62812 can reduces LPS-induced coagulation and inflammatory responses. M62812 can be used for the research of sepsis.
    M62812 (Standard)
  • HY-10581AS1
    Gatifloxacin-d4 hydrochloride 1189946-71-1 98%
    Gatifloxacin-d4 (AM-1155-d4; BMS-206584-d4; PD135432-d4) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A).
    Gatifloxacin-d4 hydrochloride
  • HY-106161S1
    Rupintrivir-d7 98%
    Rupintrivir-d7 is a deuterated labeled Rupintrivir. Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect.
    Rupintrivir-d7
  • HY-106254AR
    Vapendavir diphosphate (Standard) 1198151-75-5 98%
    Vapendavir diphosphate (Standard) is the analytical standard of Vapendavir diphosphate (HY-106254A). This product is intended for research and analytical applications. Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains.
    Vapendavir diphosphate (Standard)
  • HY-106254S1
    Vapendavir-d6 2012598-53-5 98%
    Vapendavir-d6 (BTA798-d6) is deuterium-labeled Vapendavir (HY-106254).
    Vapendavir-d6
  • HY-106257AR
    Ceftolozane TFA (Standard) 1628046-32-1
    Ceftolozane TFA (Standard) is the analytical standard of Ceftolozane TFA (HY-106257A). This product is intended for research and analytical applications. Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer.
    Ceftolozane TFA (Standard)
  • HY-106410AR
    Zabofloxacin hydrochloride (Standard) 623574-00-5 98%
    Zabofloxacin hydrochloride (Standard) is the analytical standard of Zabofloxacin hydrochloride (HY-106410A). This product is intended for research and analytical applications. Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP).
    Zabofloxacin hydrochloride (Standard)
  • HY-106542AR
    Eberconazole nitrate (Standard) 130104-32-4 98%
    Eberconazole nitrate (Standard) is the analytical standard of Eberconazole nitrate. This product is intended for research and analytical applications. Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis.
    Eberconazole nitrate (Standard)
  • HY-106594AR
    Prussian blue insoluble (Standard) 14038-43-8 98%
    Prussian blue insoluble (Standard) is the analytical standard of Prussian blue insoluble (HY-106594A). This product is intended for research and analytical applications. Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI).
    Prussian blue insoluble (Standard)
  • HY-106594BR
    Prussian blue soluble (Standard) 12240-15-2 98%
    Prussian blue soluble (Standard) is the analytical standard of Prussian blue soluble (HY-106594B). This product is intended for research and analytical applications. Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI).
    Prussian blue soluble (Standard)
  • HY-106597AR
    Pirlimycin hydrochloride (Standard) 78822-40-9
    Pirlimycin (hydrochloride) (Standard) is the analytical standard of Pirlimycin (hydrochloride). This product is intended for research and analytical applications. Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.
    Pirlimycin hydrochloride (Standard)
  • HY-106934AR
    Peldesine dihydrochloride (Standard) 2772702-10-8 98%
    Peldesine (dihydrochloride) (Standard) is the analytical standard of Peldesine (dihydrochloride). This product is intended for research and analytical applications. Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine dihydrochloride is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine dihydrochloride has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research.
    Peldesine dihydrochloride (Standard)
  • HY-106991AR
    Amustaline dihydrochloride (Standard) 210584-54-6 98%
    Amustaline (dihydrochloride) (Standard) is the analytical standard of Amustaline (dihydrochloride). This product is intended for research and analytical applications. Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products).
    Amustaline dihydrochloride (Standard)
Cat. No. Product Name / Synonyms Application Reactivity