2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1101
    Vasicinolone 84847-50-7 98%
    Vasicinolone, a natural alkaloid, exhibits anti-inflammatory and antimicrobial properties.
    Vasicinolone
  • HY-N1120
    Triptoquinone B 142937-50-6 98%
    Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells.
    Triptoquinone B
  • HY-N1143
    Tomentin 28449-62-9 98%
    Tomentin is a compound isolated from Sphaeralcea angustifolia. Tomentin inhibits the formation of λ-carrageenan footpad edema at 58 %. Tomentin inhibits the phorbol ester-induced auricular edema formation by 57 %.
    Tomentin
  • HY-N1152
    threo-Guaiacylglycerol beta-coniferyl ether 869799-76-8 98%
    threo-Guaiacylglycerol beta-coniferyl ether is a lignan that can inhibit NO production. threo-Guaiacylglycerol beta-coniferyl ether exhibits anti-neuroinflammatory activities.
    threo-Guaiacylglycerol beta-coniferyl ether
  • HY-N1162
    Tetrahydroamentoflavone 48236-96-0 98%
    Tetrahydroamentoflavone (Amentoflavanone) is a potent xanthine oxidase (XO) inhibitor. Tetrahydroamentoflavone has inhibitory activity for XO with IC50 and Ki values of 92 nM and 0.982 μM, respectively. Tetrahydroamentoflavone can be used for the research of inflammatory disorders and gout.
    Tetrahydroamentoflavone
  • HY-N1192
    Sutherlandin trans-p-coumarate 315236-68-1 98%
    Sutherlandin trans-p-coumarate is a selective γ-hydroxynitrile glycoside compound with moderate inhibitory activity on nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages (56.9% inhibition at a concentration of 25 μg/mL). Sutherlandin trans-p-coumarate can be naturally extracted from the dried aerial parts of Sorbaria sorbifolia (a plant of the genus Sorbaria in the Rosaceae family).
    Sutherlandin trans-p-coumarate
  • HY-N1219
    Stephanine 517-63-5 98%
    Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
    Stephanine
  • HY-N1221
    Stigmast-4-en-3,6-dione 23670-94-2 98%
    Stigmast-4-en-3,6-dione is an anti-inflammatory and anti-allergic agent which can be extracted from Hibiscus cannabinus and Piper betle.
    Stigmast-4-en-3,6-dione
  • HY-N1246
    Savinin 493-95-8
    Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect.
    Savinin
  • HY-N1262
    Scutebarbatine W 1312716-25-8 98%
    Scutebarbatine W is a 13-spiro subtype neo-clerodane diterpenoid. Scutebarbatine W inhibits NO production with an IC50 value of 34.7 μM.
    Scutebarbatine W
  • HY-N1263
    Scutebarbatine X 1312716-26-9 98%
    Scutebarbatine X (Compound 2) is a neo-clerodane diterpenoids isolated from Scutellaria barbatae (Labiatae) and has anti-inflammatory properties.
    Scutebarbatine X
  • HY-N1326
    Santamarine 4290-13-5 98.85%
    Santamarine (Santamarin; Balchanin) is a sesquiterpene lactone found in Artemisia scoparia. Santamarine shows anti-inflammatory, antioxidant, anticancer and anti-photoaging activities. Santamarine suppresses UVA-induced phosphorylation of JNK and p38 MAPK, nuclear translocation of phosphorylated c-Fos and c-Jun, and AP-1-mediated MMP-1 transcription and secretion. Santamarine suppresses NF-κB signaling, iNOS, COX-2, TNF-α, and IL-1β production. Santamarine inhibits thioredoxin reductase activity, induces ROS production, mitochondrial apoptosis, G2/M cell cycle arrest, and DNA damage, and reduces cancer cell growth. Santamarine can be used for the photoaging, inflammatory diseases and cancer.
    Santamarine
  • HY-N1337
    Rubelloside B 167875-39-0 98%
    Rubelloside B, a triterpenoid glycoside, can be isolated from the roots of Adina rubella. Rubelloside B shows Immunological Enhancement.
    Rubelloside B
  • HY-N1418
    (S)-(-)-Tetrahydroberberine 5096-57-1 98%
    (S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity.
    (S)-(-)-Tetrahydroberberine
  • HY-N1494
    (+)-14-Deoxy-ε-caesalpin 279683-46-4 98%
    (+)-14-Deoxy-ε-caesalpin (14-Deoxy-ε-caesalpin), a cassane diterpenoid, inhibits nitric oxide (NO) production release of RAW 264.7 cells stimulated by Lipopolysaccharide (LPS).
    (+)-14-Deoxy-ε-caesalpin
  • HY-N1531
    Randaiol 87562-14-9 98%
    Randaiol is an antioxidant that can be isolated from the stem bark of Magnolia officinalis. Randaiol inhibits LPS-induced NO production and has anti-inflammatory and antioxidant activities.
    Randaiol
  • HY-N1533
    28-O-β-D-Glucopyranosyl pomolic acid 83725-24-0 98%
    28-O-β-D-Glucopyranosyl pomolic acid is a urokinase plasminogen activator inhibitor with IC50 at 37.82 μM.
    28-O-β-D-Glucopyranosyl pomolic acid
  • HY-N1546
    Protoplumericin A 80396-57-2 98%
    Protoplumericin A is a bioactive ingredient of Plumeria obtusa L. attenuates. Protoplumericin A mitigated lipopolysaccharide (LPS) -induced acute lung injury in mice. Protoplumericin A can be used to study the LPS-induced anti-inflammatory effect .
    Protoplumericin A
  • HY-N1547
    Prudomestin 3443-28-5 98.68%
    Prudomestin, isolated from the heartwood of Prunus domestica, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6 µM).
    Prudomestin
  • HY-N1625
    1-Hydroxy-2-methylanthraquinone 6268-09-3 98%
    1-Hydroxy-2-methylanthraquinone exhibits antimicrobial, antioxidant, pesticidal, and anti-inflammatory activities.
    1-Hydroxy-2-methylanthraquinone
Cat. No. Product Name / Synonyms Application Reactivity