2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P990304A
    Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a) 98%
    Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a) is a mouse-derived IgG2a κ antibody inhibitor that targets mouse 4-1BBL/CD137L. Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a) is a chimeric version of the original TKS-1 antibody (HY-P990304). The variable domain sequences are identical to the original TKS-1 but the constant region sequences have been switched from rat IgG2a to mouse IgG2a. Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a) reacts with mouse 4-1BB ligand (4-1BBL). Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a) can be used for the researches of cancer, infection, inflammation and immunology.
    Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1-Mouse IgG2a)
  • HY-P990304B
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 98%
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a mouse-derived IgG1 κ antibody inhibitor that targets mouse 4-1BBL/CD137L. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a chimeric version of the original TKS-1 antibody (HY-P990304). The variable domain sequences are identical to the original TKS-1 but the constant region sequences have been switched from rat IgG2a to mouse IgG1. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) reacts with mouse 4-1BB ligand (4-1BBL). Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) can be used for the researches of cancer, infection, inflammation and immunology.
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1)
  • HY-W001083R
    3-Hydroxyphenylacetic acid (Standard) 621-37-4 98%
    3-Hydroxyphenylacetic acid (Standard) is the analytical standard of 3-Hydroxyphenylacetic acid (HY-W001083). This product is intended for research and analytical applications. 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders.
    3-Hydroxyphenylacetic acid (Standard)
  • HY-W002004S
    4-Amino-TEMPO-d17,15N 97461-87-5 98%
    4-Amino-TEMPO-d17,15N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17,15N) is the deuterium labeled 4-Amino-TEMPO-d17 (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others.
    4-Amino-TEMPO-d17,15N
  • HY-W002116S
    Methyl syringate-d6 1182838-09-0 98%
    Methyl syringate-d6 is the deuterium labeled Methyl syringate. Methyl syringate is a selective TRPA1 agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis.
    Methyl syringate-d6
  • HY-W002484R
    3-Hydroxy-4-methoxyacetophenone (Standard) 6100-74-9 98%
    3-Hydroxy-4-methoxyacetophenone (Standard) is the analytical standard of 3-Hydroxy-4-methoxyacetophenone. This product is intended for research and analytical applications. 3-Hydroxy-4-methoxyacetophenone(Acetoisovanillone; Isoacetovanillone) is an active compound isolated from P. spinosa. Isoacetovanillone possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.
    3-Hydroxy-4-methoxyacetophenone (Standard)
  • HY-W003467R
    Rabeprazole Sulfide (Standard) 117977-21-6 98%
    Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide (HY-W003467). This product is intended for research and analytical applications. Rabeprazole Sulfide is a sulfide metabolite of Rabeprazole (HY-B0656). Rabeprazole Sulfide inhibits Helicobacter pylori motility. Rabeprazole Sulfide can be used for the research of Helicobacter pylori infection.
    Rabeprazole Sulfide (Standard)
  • HY-W003607R
    3-O-Ethyl-L-ascorbic acid (Standard) 86404-04-8 98%
    3-O-Ethyl-L-ascorbic acid (Standard) is the analytical reference standard for 3-O-Ethyl-L-ascorbic acid. 3-O-Ethyl-L-ascorbic acid is a stable derivative of vitamin C and a cosmetic tyrosinase inhibitor. 3-O-Ethyl-L-ascorbic acid has antioxidant, anti-aging, and skin-whitening activities. 3-O-Ethyl-L-ascorbic acid is often used in the study of cosmetic.
    3-O-Ethyl-L-ascorbic acid (Standard)
  • HY-W004049S
    3-Hydroxybenzoic acid-d4
    3-Hydroxybenzoic acid-d4 is the deuterium labeled 3-Hydroxybenzoic acid (HY-W004049). 3-Hydroxybenzoic acid is an orally active endogenous metabolite. 3-Hydroxybenzoic acid is an agonist for GPR81 and GPR109A. 3-Hydroxybenzoic acid acts as stress response desensitizers. 3-Hydroxybenzoic acid can be used for anti-inflammatory and analgesic study.
    3-Hydroxybenzoic acid-d4
  • HY-W004295S
    1-Pentadecanol-d31 349553-87-3 98%
    1-Pentadecanol-d31 is the deuterium labeled 1-Pentadecanol. 1-Pentadecanol is a naturally occurring antiacne agent.
    1-Pentadecanol-d31
  • HY-W005327R
    1-Hydroxy-2-butanone (Standard) 5077-67-8
    1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone. This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].
    1-Hydroxy-2-butanone (Standard)
  • HY-W007328S
    5-Methoxyindole-d3 90663-68-6
    5-Methoxyindole-d3 is the deuterium labeled 5-Methoxyindole (HY-W007328). 5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.
    5-Methoxyindole-d3
  • HY-W007346R
    m-Anisaldehyde (Standard) 591-31-1 98%
    m-Anisaldehyde (Standard) is the analytical standard of m-Anisaldehyde (HY-W007346). This product is intended for research and analytical applications. m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy.
    m-Anisaldehyde (Standard)
  • HY-W007346S
    m-Anisaldehyde-d3 1219795-07-9 98%
    m-Anisaldehyde-d3 is the deuterium labeled m-Anisaldehyde (HY-W007346). m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy.
    m-Anisaldehyde-d3
  • HY-W007539R
    2,4-Dihydroxybenzaldehyde (Standard) 95-01-2 98%
    2,4-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,4-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions.
    2,4-Dihydroxybenzaldehyde (Standard)
  • HY-W008440S
    DL-Cycloserine-15N,d3 1219176-26-7 98%
    DL-Cycloserine-15N,d3 is the deuterium labeled DL-Cycloserine (HY-W008440). DL-Cycloserine is an orally active aminotransferase inhibitor. DL-Cycloserine exhibits completely opposite effects on the activity of monoamine oxidase in different tissues. DL-Cycloserine can be used for the research of pulmonary tuberculosis, psychosomatic diseases, and depressive states.
    DL-Cycloserine-15N,d3
  • HY-W008613R
    Pamoic acid (Standard) 130-85-8 98%
    Pamoic acid (Standard) is the analytical standard of Pamoic acid. This product is intended for research and analytical applications. Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. Pamoic acid exhibits neuroprotective and anti-inflammatory properties.
    Pamoic acid (Standard)
  • HY-W008614R
    Lansoprazole sulfone (Standard) 131926-99-3
    Lansoprazole sulfone (AG-1813) (Standard) is the analytical standard of Lansoprazole sulfone (HY-W008614). This product is intended for research and analytical applications. Lansoprazole sulfone, Lansoprazole (HY-13662) metabolite, is a H+, K+-ATPase inhibitor. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
    Lansoprazole sulfone (Standard)
  • HY-W008614S
    Lansoprazole sulfone-d4 1184999-77-6 98%
    Lansoprazole sulfone (AG-1813)-d4 is the deuterium labeled Lansoprazole sulfone (HY-W008614). Lansoprazole sulfone, Lansoprazole (HY-13662) metabolite, is a H+, K+-ATPase inhibitor. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
    Lansoprazole sulfone-d4
  • HY-W008923R
    Doxycycline monohydrate (Standard) 17086-28-1
    Doxycycline monohydrate (Standard) is the analytical standard of Doxycycline monohydrate (HY-W008923). Doxycycline monohydrate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline monohydrate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline monohydrate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline monohydrate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline monohydrate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline monohydrate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers.
    Doxycycline monohydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity