2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-P990844
    Anti-GC1q R/C1QBP Antibody (60.11) 98%
    Anti-GC1q R/C1QBP Antibody (60.11) is a kind of mouse IgG1 κ chimeric antibody inhibitor, targeting to human GC1q R/C1QBP. Anti-GC1q R/C1QBP Antibody (60.11) can neutralize GC1q R. Anti-GC1q R/C1QBP Antibody (60.11) can be used for the researches of cancer, infection and inflammation, such as MDA231 tumor and S. aureus induced infective endocarditis (IE).
    Anti-GC1q R/C1QBP Antibody (60.11)
  • HY-P990847
    Anti-E-Selectin Antibody (CL2) 98%
    Anti-E-Selectin Antibody (CL2) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human E-Selectin. Anti-E-Selectin Antibody (CL2) reacts with human E-selectin also known as CD62E, endothelial-leukocyte adhesion molecule 1 (ELAM-1), and leukocyte-endothelial cell adhesion molecule 2 (LECAM2). Anti-E-Selectin Antibody (CL2) directly blocks the binding of E selectin to carbohydrate ligands. Anti-E-Selectin Antibody (CL2) can be used for the detection of flow cytometry.
    Anti-E-Selectin Antibody (CL2)
  • HY-P990851
    Anti-c-Kit/CD117 Antibody (SR-1) ≥99.0%
    Anti-c-Kit/CD117 Antibody (SR-1) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human c-Kit/CD117. Anti-c-Kit/CD117 Antibody (SR-1) binds to the extracellular domain of human c-Kit (also known as CD117) and blocks stem cell factor (SCF) binding to CD117. Anti-c-Kit/CD117 Antibody (SR-1) can be used for the researches of cancer and immunology, such as gastrointestinal stromal tumor (GIST) and xenograft.
    Anti-c-Kit/CD117 Antibody (SR-1)
  • HY-P990948
    Trosunilimab 2550297-60-2 98%
    HY-P990948 is an ITGA4_ITGB7-targeting IgG1κ type chimeric humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).
    Trosunilimab
  • HY-P991006
    Lofacimig 2857858-76-3 98%
    HY-P991006 is an FXI/PTA-targeting VH-VH-G1(h-CH2-CH3) dimer type bispecific antibody.
    Lofacimig
  • HY-P991111
    Anti-Mouse TIGIT Antibody (10A7) 98.37%
    Anti-Mouse TIGIT Antibody (10A7) is a mouse IgG2 monoclonal antibody that targets TIGIT. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978).
    Anti-Mouse TIGIT Antibody (10A7)
  • HY-P991121
    Baloncibart 2988795-75-9 98%
    Baloncibart is a human IgG4K antibody targeting NPR1. The corresponding isotype control is: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Baloncibart
  • HY-P99123A
    Anti-Mouse CD28 (LALA-PG) Antibody (D665) 98%
    Anti-Mouse CD28 (LALA-PG) Antibody (D665) is an anti-mouse CD28 IgG2a monoclonal antibody. Anti-Mouse CD28 (LALA-PG) Antibody (D665) is a chimeric antibody of the original D665 antibody (HY-P990793). Anti-Mouse CD28 (LALA-PG) Antibody (D665) contains the LALA-PG mutation region. Anti-Mouse CD28 Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for research on neurological conditions, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD).
    Anti-Mouse CD28 (LALA-PG) Antibody (D665)
  • HY-P991255
    VRDN-002 98%
    VRDN-002 is a human monoclonal antibody (mAb) targeting IGF1R/CD221. VRDN-002 reduces inflammation and proptosis in thyroid eye disease (TED). VPI-2690B can be used in Graves ophthalmopathy research.
    VRDN-002
  • HY-P991288
    OPR-003 98%
    OPR-003 is a human monoclonal antibody targeting IL-6. OPR-003 can be used in the research of Haematological malignancies and Rheumatoid arthritis.
    OPR-003
  • HY-P991313
    PD-360324 98%
    PD-360324 is a human monoclonal antibody (mAb) targeting CSF1/M-CSF. PD-360324 can be used in cutaneous lupus erythematosus, pulmonary sarcoidosis and rheumatoid arthritis research.
    PD-360324
  • HY-P991341
    FF-21101
    FF-21101 is a human IgG1 monoclonal antibody (mAb) targeting CDH3/P-cadherin. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    FF-21101
  • HY-P991477
    HFB-100204 98%
    HFB-100204 is a human monoclonal antibody (mAb) targeting CXCR5. HFB-100204 reduces CXCR5+ immune cells, including B cells and Tfh cells, in the blood and spleen of hCXCR5 knockout mice. HFB-100204 can be used in autoimmune diseases research.
    HFB-100204
  • HY-P991502
    Armenian hamster IgG1 kappa, Isotype Control 98%
    Armenian hamster IgG1 kappa, Isotype Control, a Armenian hamster monoclonal antibody, is an isotype control for Armenian hamster IgG1 kappa antibody.
    Armenian hamster IgG1 kappa, Isotype Control
  • HY-P991532
    AT002 98%
    AT002 (CBAS-173, EJ212/007-Cl2-5) is a recombinant human IgG1 monoclonal antibody. AT002 targets the cell surface protein activated leukocyte adhesion molecule (ALCAM)/CD166. AT002 can be used in the research of cancer, autoimmune diseases and inflammatory diseases.
    AT002
  • HY-P991543
    BTI-322 339181-10-1 98.15%
    BTI-322 is a human IgG1κ antibody directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease.
    BTI-322
  • HY-P991629
    C1 Esterase Inhibitor (Human)
    C1 Esterase Inhibitor (Human) is a C1 Esterase inhibitor derived from human plasma. C1 Esterase Inhibitor (Human), a glycoprotein, is a serum protease inhibitor (serpin) that binds covalently and inactivates C1r, C1s, and mannan-binding protein-associated proteases (MASPs). C1 Esterase Inhibitor (Human) has anti-inflammatory effects. C1 Esterase Inhibitor (Human) can be used to prevent angioedema attacks associated with hereditary angioedema.
    C1 Esterase Inhibitor (Human)
  • HY-P991651
    MEDI4212 98%
    MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research.
    MEDI4212
  • HY-P991745
    Anti-Mouse CCR2 Antibody (C2Mab-6) 98%
    Anti-Mouse CCR2 Antibody (C2Mab-6) is raised against and binds to the N-terminal sequence of CCR2. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979).
    Anti-Mouse CCR2 Antibody (C2Mab-6)
  • HY-P991775
    Anti-Rat CTLA-4 Antibody (WKH203) 98%
    Anti-Rat CTLA-4 Antibody (WKH203) reacts with rat CTLA-4. Anti-Rat CTLA-4 Antibody (WKH203) binds to the CTLA-4 protein disrupts the key signaling mechanisms linked to the suppression of T cell activity, triggering T cells readily and enhancing the immune system’s capacity to identify and eliminate cancer. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-Rat CTLA-4 Antibody (WKH203)
Cat. No. 상품명 / Synonyms Application Reactivity