1. GPCR/G Protein
  2. CaSR
  3. Strontium Ranelate

Strontium Ranelate (Synonyms: Distrontium renelate; S12911)

Cat. No.: HY-17397 Purity: 99.16%
Handling Instructions

Strontium ranelate(S12911) stimulates the calcium sensing receptors (CaSR) and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation.

For research use only. We do not sell to patients.

Strontium Ranelate Chemical Structure

Strontium Ranelate Chemical Structure

CAS No. : 135459-87-9

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Description

Strontium ranelate(S12911) stimulates the calcium sensing receptors (CaSR) and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation. IC50 value: Target: CaSR Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Strontium Ranelate acts by increasing bone formation and decreasing bone resorption, thus rebalancing bone turnover in favour of bone formation, an effect that results in increased bone mass and strength. Commonly used as an antiosteoporotic. Strontium Ranelate has shown efficacy in preventing early postmenopausal bone loss and reducing the risk of hip fracture in women with postmenopausal osteoporosis.

Clinical Trial
Molecular Weight

513.49

Formula

C₁₂H₆N₂O₈SSr₂

CAS No.

135459-87-9

SMILES

O=C(O[Sr]OC(C1)=O)C2=C1C(C#N)=C(N3CC(O[Sr]OC(C3)=O)=O)S2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Strontium Ranelate
Cat. No.:
HY-17397
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