135459-87-9
Chemical Structure
Strontium Ranelate
Synonym(s): Distrontium renelate; S12911
- CAS No.: 135459-87-9
- Formula:C12H6N2O8SSr2
- Molecular Weight:513.49
IUPAC Name: strontium 2,2'-((5-carboxylato-4-(carboxylatomethyl)-3-cyanothiophen-2-yl)azanediyl)diacetate
InChIKey: XXUZFRDUEGQHOV-UHFFFAOYSA-J
SMILES: O=C(O[Sr]OC(C1)=O)C2=C1C(C#N)=C(N3CC(O[Sr]OC(C3)=O)=O)S2
Biological Activity: Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Strontium Ranelate | 99.30% | Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Strontium Ranelate (Standard) | ≥98% | Strontium Ranelate (Standard) is the analytical standard of Strontium Ranelate. This product is intended for research and analytical applications. Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Bonnelye E, Chabadel A, Saltel F, Jurdic P. Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone. 2008 Jan;42(1):129-38. Epub 2007 Sep 12. [Content Brief]
- [2]. Marie PJ. Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol. 2006 Jun;18 Suppl 1:S11-5. [Content Brief]
