2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Apoptosis
  3. EGFR Apoptosis
  4. EGFR-IN-105

EGFR-IN-105 (Compound 5b) is an EGFR2 inhibitor with an IC50 value of 0.68 μM. EGFR-IN-105 exhibits anticancer activity and can induce apoptosis in cancer cells, which is used in the research of pancreatic cancer.

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EGFR-IN-105 Chemical Structure

EGFR-IN-105 Chemical Structure

CAS No. : 831244-98-5

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EGFR-IN-105 Related Antibodies

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Description

EGFR-IN-105 (Compound 5b) is an EGFR2 inhibitor with an IC50 value of 0.68 μM. EGFR-IN-105 exhibits anticancer activity and can induce apoptosis in cancer cells, which is used in the research of pancreatic cancer[1].

IC50 & Target

ErbB2

0.68 μM ()

Molecular Weight

374.54

Formula

C20H30N4OS
CAS No.
SMILES

O=C(NC1=C(C#N)C(CCC(C(C)(C)C)C2)=C2S1)CN3CCN(C)CC3
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Purity & Documentation
References
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EGFR-IN-105 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-105831244-98-5EGFRApoptosisEpidermal growth factor receptorErbB-1HER1Mia PaCa-2cancerpancreatic cancerInhibitorinhibitorinhibit

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