1. Saccharides and Glycosides
  2. Sucrose

Sucrose (Synonyms: D-(+)-Saccharose)

Cat. No.: HY-B1779 Purity: >98.0%
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Sucrose is a disaccharide which is composed of two monosaccharides, glucose and fructose.

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Sucrose Chemical Structure

Sucrose Chemical Structure

CAS No. : 57-50-1

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Based on 1 publication(s) in Google Scholar

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Description

Sucrose is a disaccharide which is composed of two monosaccharides, glucose and fructose.

In Vivo

Sucrose is a disaccharide which is composed of two monosaccharides, glucose and fructose. Compare to chow-feeding, high-energy (HE)-feeding results in an overall decreased preference for Sucrose solutions in both strains. Specifically, obesity-prone (OP) rats prefer 0.3 M and 1.0 M Sucrose solutions less during HE-feeding relative to chow-feeding (P=0.046 and P=0.012, respectively). As well, obesity-resistant (OR) rats exhibit decreased preferences for 0.01 M, 0.03 M, and 1.0 M Sucrose when HE-fed compare to chow-fed counterparts (P<0.0001, P=0.043, and P=0.013, respectively). Chow-fed OP rats consume significantly less of 0.03 and 0.1 M Sucrose solutions relative to OR animals (P<0.0001, for both) while HE-fed OP rats consume less of a 0.1 M Sucrose solution only (P<0.05), compare to HE-fed OR rats[1].

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (292.14 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9214 mL 14.6071 mL 29.2141 mL
5 mM 0.5843 mL 2.9214 mL 5.8428 mL
10 mM 0.2921 mL 1.4607 mL 2.9214 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[1]

A total of 66 male 8-wk-old Sprague-Dawley obesity-prone (OP) and obesity-resistant (OR) rats (n = 38 per each phenotype), weighing 275 g and 210 g respectively, are used in this study. After recovery and attaining pre-surgical weights, rats undergo three training trials of 60-min sham feeding sessions with 0.03 M Sucrose solution. During testing, rats are briefly deprived of water (0900 to 1600 h) but not food, and are tested for 1 h (1400 to1500 h) sham intake of 0.03 M Sucrose solution until a stable baseline is achieved. Afterwards, rats are sham fed one of three Sucrose solutions (0.03, 0.3, and 1.0 M) in random order, every other day, with each concentration tested at least twice. Sucrose intake is individually recorded every 5 min for 60 min[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

342.30

Formula

C₁₂H₂₂O₁₁

CAS No.

57-50-1

SMILES
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Room temperature in continental US; may vary elsewhere

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Sucrose
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HY-B1779
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Sucrose

Cat. No.: HY-B1779