Fungal

Related Products

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.

Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Fungal Related Products (2637)
Antibodies (1)
Related Compound Screening Libraries (1)

By Effects:	Inhibitors (2349)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-N12683

Phaseollinisoflavan	Inhibitor
Phaseollinisoflavan, an antifungal isoflavonoid, is a phytoalexin.

HY-109040R

Quilseconazole (Standard)	Inhibitor
Quilseconazole (Standard) is the analytical standard of Quilseconazole (HY-109040). This product is intended for research and analytical applications. Quilseconazole (VT-1129) is an orally active, highly selective fungal cytochrome P450 enzyme Cyp51 inhibitor that can cross the blood-brain barrier. Quilseconazole prevents the synthesis of ergosterol, an important component of the fungal cell membrane, by inhibiting Cyp51. Quilseconazole has minimal effects on human CYP enzymes. Quilseconazole has antifungal activity and can be used in the study of cryptococcal meningitis and other diseases.

HY-N12990

Myrigalone A	Inhibitor
Myrigalone A (MyA) is a plant ethylene biosynthesis inhibitor and natural herbicide. Myrigalone A possesses antioxidant, antifungal, and antimicrobial activities. Myrigalone A interferes with auxin homeostasis during seed germination. Myrigalone A delays seed germination, inhibits the formation of roots, hypocotyls, and root hairs, and causes developmental delay in specific organisms. Myrigalone A triggers the induction of detoxification programs, alters the metabolism of gibberellins, cis-(+)-12-oxophytodienoic acid, and jasmonic acid, disrupts the antioxidant system and oxidative signaling, and impairs the function of aquaporins and water uptake in imbibed seeds. Myrigalone A can be used in studies related to herbicides and plant growth regulators.

HY-N14260

Hypelcin A-II	Inhibitor
Hypelcin A-II has anti-Gram-negative bacterial and fungal activity.

HY-N15326

Phytoalexine	Inhibitor
Phytoalexine (Compound 8) is a phytoalexin found in wasabi with antifungal activity against fungi such as Phoma lingam and Phoma wasabiae. Phytoalexine inhibits spore germination and mycelial growth of fungi. Phytoalexine is promising for research of pesticides against plant fungal diseases.

HY-W774918

Oxaziclomefone	Inhibitor	99.43%
Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-149738

FXh	Inhibitor
FXh is a functionalized hapten activated by incubation with N, N′-disuccinimidyl carbonate, and Et3N in acetonitrile at 0 °C. FXh can improve the affinity of antigens.

HY-120729R

Pyrazophos (Standard)	Inhibitor
Pyrazophos (Standard) is the analytical standard of Pyrazophos. This product is intended for research and analytical applications. Pyrazophos (Curamil) is a slightly systemic fungicide against the powdery mildew on crops and cereals. Pyrazophos is widely used in Greece to control diseases caused by Erysiphe spp., Sphaerotheca spp., Leveillula spp. and Oidium spp..

HY-N6829R

Retusin (Standard)	Inhibitor
Retusin (Quercetin-3,3',4',7-tetramethylether) (Standard) is the analytical standard of Retusin. This product is intended for research and analytical applications. Retusin is a tyrosinase inhibitor, with IC₅₀ values of 50.9 μM and 51.8 μM against mushroom and intracellular tyrosinase, respectively. Retusin also acts as a free radical scavenger, melanogenesis inhibitor, anti-apoptosis agent, neuroprotective agent, antiemetic, antifungal agent, and antiviral agent. Retusin scavenges ABTS•⁺ and DPPH• free radicals. Retusin can be used in studies related to hyperpigmentation, vomiting, Aspergillus niger infection, and COVID-19 infection.

HY-N7237

Stichloroside B1	Inhibitor
Stichloroside B1 is a class of antifungal triterpenoid oligosaccharide isolated from the sea cucumber Stichopus chloronotus (BRANDT).

HY-116686

Inz-1	Inhibitor
Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC₅₀=8.092 μM) over humans (IC₅₀=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in the pathogenic fungus Candida albicans.

HY-N14746

Elizabethin	Inhibitor
Elizabethin has antifungal activity.

HY-111912R

Tribenuron-methyl (Standard)	Inhibitor
Tribenuron-methyl (Standard) is the analytical standard of Tribenuron-methyl. This product is intended for research and analytical applications. Tribenuron-methyl, a sulfonylurea herbicide agent, can be used as the fungicide agent. Tribenuron-methyl plays an important role in controlling the weeds and diseases in wheat field.

HY-N14968

Enniatin F	Inhibitor
Enniatin F has insecticidal and antifungal activity. Enniatin F also can inhibit acyl-CoA, cholesterol acyltransferase (ACAT).

HY-B2056R

Triforine (Standard)	Inhibitor
Triforine (Standard) is the analytical standard of Triforine. This product is intended for research and analytical applications. Triforine (CELA W 524), a systemic fungicide, was shown to display a moderate to distinct fungitoxic activity in vitro towards several pathogenic and non-pathogenic fungi.

HY-N14199

Mathemycin B	Inhibitor
Mathemycin B has an inhibitory effect on pathogenic fungi. Mathemycin B inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL).

HY-B0914AR

10-Undecenoic acid zinc salt (Standard)	Inhibitor
10-Undecenoic acid (zinc salt) (Standard) is the analytical standard of 10-Undecenoic acid (zinc salt). This product is intended for research and analytical applications. 10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa.

HY-137085

Antibiotic AB023b	Inhibitor
Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum.

HY-W016806R

Sodium methylparaben (Standard)	Inhibitor
Sodium methylparaben (Standard) is the analytical standard of Sodium methylparaben. This product is intended for research and analytical applications. Sodium methylparaben (Sodium methyl 4-hydroxybenzoate) is an antifungal agent.