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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Produits associés (3817):

Cat. No. Nom du produit Effet Pureté Chemical Structure
  • HY-N7735
    6-Methoxyspirotryprostatin B
    6-Methoxyspirotryprostatin B is a natural alkaloid.
    6-Methoxyspirotryprostatin B
  • HY-N19296
    Blapsin B
    Blapsin B is a potent 14-3-3 inhibitor and a naturally occurring compound from Blaps japanensis. Blapsin B potently inhibits 14-3-3 protein-protein interactions (PPIs) with an IC50 value of 10.0 μM in the ELISA assay and 2.5 μM in the FP assay, respectively. Blapsin B modulates signaling pathways involved in cell proliferation and transformation. Blapsin B can be used for cancer research.
    Blapsin B
  • HY-N17482
    Ligustilidiol
    Ligustilidiol is a natural product that can be found in Chuanxiong.
    Ligustilidiol
  • HY-N13735
    β-Glucosyl indole-3-carboxylate
    β-Glucosyl indole-3-carboxylate is a natural alkaloid.
    β-Glucosyl indole-3-carboxylate
  • HY-N16845
    1-O-Methylclausenolide
    1-O-Methylclausenolide is a natural triterpene.
    1-O-Methylclausenolide
  • HY-106366
    Siagoside
    Siagoside is an inner ester of Ganglioside GM1 (HY-N10546). Siagoside selectively attenuates morphological and functional striatal impairments induced by transient forebrain ischemia in rats. Siagoside can be used for the research of neurological disease, such as acute cerebral ischemia.
    Siagoside
  • HY-N17094
    Suffruticosol C
    Suffruticosol C is a natural phenolic compound.
    Suffruticosol C
  • HY-182603
    BO-653
    BO-653 is an orally active anti-atherosclerotic antioxidant that exhibits high binding affinity for LDL. BO-653 scavenges linoleic acid peroxyl radicals, inhibits lipid peroxidation during the auto-oxidation of linoleic acid, and potently suppresses LDL oxidation. BO-653 inhibits Hepatitis C Virus (HCV) replication in a concentration-dependent manner, with an IC50 of 36.0 μM against the HCV subgenomic replicon in FLR3-1 cells. BO-653 demonstrates significant anti-atherosclerotic effects in various animal models, including the Watanabe heritable hyperlipidemic rabbit. BO-653 is suitable for use in research related to atherosclerosis and Hepatitis C Virus infection.
    BO-653
  • HY-176967
    N-Cholyl-L-glutamic acid
    N-Cholyl-L-glutamic acid (GluCA) is a Cholic acid (HY-N0324) conjugated with L-glutamic acid (HY-14608). N-Cholyl-L-glutamic acid increases expression of PXR and downstream PXR-target gene Cyp3a11. N-Cholyl-L-glutamic acid can be used in the research of Crohn's disease.
    N-Cholyl-L-glutamic acid
  • HY-149094
    Neuroprotective agent 1
    Neuroprotective agent 1 (2), a promising neuroprotective agent for the study of ischemic stroke, shows promising neuroprotective activity with the EC50 value of 16.07 μM in the model of glutamate-induced excitotoxicity and 19.30 μM in the model of H2O2-induced oxidative damage.
    Neuroprotective agent 1
  • HY-N16806
    Yunnancoronarin B
    Yunnancoronarin B is a natural diterpene.
    Yunnancoronarin B
  • HY-N18122
    Cimiside A
    Cimiside A is a 9,19-cycloartane triterpene monoglycoside.Cimiside A can be found in the rhizome of Cimicifuga foetida.
    Cimiside A
  • HY-N17052
    Pyridylpaeoniflorin
    Pyridylpaeoniflorin is a natural terpenoid.
    Pyridylpaeoniflorin
  • HY-N17401
    (22E,24R)-Ergosta-7,9(11),22-triene-3β,5α,6β-triol
    (22E,24R)-Ergosta-7,9(11),22-triene-3β,5α,6β-triol is a natural product that can be found in Claviceps purpurea.
    (22E,24R)-Ergosta-7,9(11),22-triene-3β,5α,6β-triol
  • HY-N17071
    16-Oxo-21-episerratenediol
    16-Oxo-21-episerratenediol is a natural triterpene.
    16-Oxo-21-episerratenediol
  • HY-N19726
    Capsianoside IV
    Capsianoside IV is a monomeric acyclic diterpenoid glycoside and geranyl linalool derivative, which can be isolated from the fruits of Capsicum annuum var. grossum (bell pepper).
    Capsianoside IV
  • HY-180426
    4-Chloronaphthalimide
    4-Chloronaphthalimide is a derivative of Naphthalimide and can be used as a drug intermediate.
    4-Chloronaphthalimide
  • HY-N12393
    11-Methoxyuncarine C
    11-Methoxyuncarine C (Caboxine B) is a natural alkaloid.
    11-Methoxyuncarine C
  • HY-W674624
    WAY-312858
    		98.0%
    WAY-312858 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-312858
  • HY-135020
    AC-24,055
    AC-24,055 is an active compound.
    AC-24,055