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  3. Drug Derivative
  4. Yunnancoronarin B

Yunnancoronarin B is a natural diterpene.

For research use only. We do not sell to patients.

Yunnancoronarin B

Yunnancoronarin B Chemical Structure

CAS No. : 162762-94-9

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Yunnancoronarin B Related Antibodies

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Description

Yunnancoronarin B is a natural diterpene.

In Vitro

Yunnancoronarin B (Compound 4) (5 μL in 0.5%-10% DMSO; 4-5 days) shows cytotoxic activity against NCI-H187 and Vero cells (IC50 = 44.57 μM for NCI-H187, 106.21 μM for Vero)[1].
Yunnancoronarin B (Compound 3) (3 days) potently inhibits the growth of lung adenocarcinoma A549 cells and leukemia K562 cells in vitro (IC50 = 0.92 μM for A549, 9.54 μM for K562)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Yunnancoronarin B Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: NCI-H187 cells, Vero cells
Concentration: 5 μL in 10% DMSO for NCI-H187; 5 μL in 0.5% DMSO for Vero
Incubation Time: 5 days (NCI-H187); 4 days (Vero)
Result: Exhibited cytotoxic activity against NCI-H187 cells with an IC₅₀ of 44.57 μM and against Vero cells with an IC₅₀ of 106.21 μM, resulting in a selectivity index of 2.4
Molecular Weight

316.43

Formula

C20H28O3
CAS No.
SMILES

C[C@@]12[C@]([C@@H](CC([C@@H]2/C=C/C3=CCOC3=O)=C)O)([H])C(C)(CCC1)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Yunnancoronarin B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Yunnancoronarin B162762-94-9Drug DerivativeDrug derivativeVero cellsK562 cellshuman small cell lung cancerA549 cellsNCI-H187lung adenocarcinomanon-cancerous cellsleukemia cellscancercytotoxic activitycancer cellslabdane-type diterpenoidInhibitorinhibitorinhibit

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HY-N16806
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