6-Methoxyspirotryprostatin B
6-Methoxyspirotryprostatin B is a natural alkaloid.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1031727-28-2
- Fòrmula: C22H23N3O4
- Peso molecular:393.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
8.29 μM
Compound: 1
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 18505285] |
| HL-60 | IC50 |
9.71 μM
Compound: 1
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 18505285] |
| Jurkat | IC50 |
21.1 μM
Compound: 13
|
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay
|
[PMID: 20303767] |
| K562 | IC50 |
41 μM
Compound: 7
|
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 19256529] |
In Vitro
6-Methoxyspirotryprostatin B (1 μM-10 mM; 72 h) weakly inhibits A-549 cell viability (IC50 = 8.29 μM) and slightly inhibits HL-60 cell viability (IC50 = 9.71 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1031727-28-2
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Peso molecular 393.44
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Fòrmula C22H23N3O4
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SMILES
O=C([C@]([C@@H]1/C=C(C)\C)2C=C(N1C3=O)C(N4[C@@]3([H])CCC4)=O)NC5=C2C=CC(OC)=C5
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Structure Classification
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Initial Source
Aspergillus sydowi
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)