2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3816):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N18345A
    Paliurusene A
    Paliurusene A is a betulinic acid-type pentacyclic triterpenoid that can be isolated from the leaves of Paliurus ramosissimus (Lour.) Poir. Paliurusene A induces growth inhibition of human hepatoma cells in vitro. Paliurusene A is applicable to research related to liver cancer.
    Paliurusene A
  • HY-121934
    BH3I-2'
    BH3I-2' is the BH3I-2 analogue. BH3I-2 is a Bcl-2 family inhibitor. BH3I-2' can be used for various studies.
    BH3I-2'
  • HY-N16702
    8-Demethyleucalyptin
    8-Demethyleucalyptin is a natural flavonoid.
    8-Demethyleucalyptin
  • HY-182012
    DT-678
    DT-678 is an orally active antiplatelet and antithrombotic inhibitor. DT-678 is a conjugate formed by linking the active metabolite of Clopidogrel (HY-15283) with 3-nitropyridine-2-thiol via a mixed disulfide bond. DT-678 does not rely on CYP2C19 for activation, and directly releases active substances via thiol exchange reactions in vivo, exhibiting superior efficacy over Clopidogrel. DT-678 can be used in research related to acute coronary syndrome and thrombosis.
    DT-678
  • HY-121307
    Gliamilide
    Gliamilide is an active and well tolerated sulfamylurea derivative and displays a very short plasma half-life. Gliamilide is promising for research of maturity-onset diabetic deseases.
    Gliamilide
  • HY-164641
    GPR34 agonist 1
    GPR34 agonist 1 (Compound M1), a lysophosphatidylserine analogue, is an efficient GPR34 agonist.
    GPR34 agonist 1
  • HY-115850
    Ornithine-methotrexate
    Ornithine-methotrexate is an active compound.
    Ornithine-methotrexate
  • HY-105629
    Populin
    Populin, a Salicin (HY-N0149) derivative, is a glucoside found in the fallen leaves of Populus alba × P. berolinensis.
    Populin
  • HY-133649
    Dibromochloroacetaldehyde
    Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity.
    Dibromochloroacetaldehyde
  • HY-N13789
    Physaminimin C
    Physaminimin C is a natural steroid.
    Physaminimin C
  • HY-135876
    γ-Elemene
    γ-Elemene is a natural product that can be found in olives.
    γ-Elemene
  • HY-N16885
    Dodovisone A
    Dodovisone A is a natural flavonoid.
    Dodovisone A
  • HY-122084
    (3β,5α)-Androstan-3-amine hydrochloride
    (3β,5α)-Androstan-3-amine (hydrochloride) is an active compound.
    (3β,5α)-Androstan-3-amine hydrochloride
  • HY-N17534
    3,5-O-Dicaffeoyl-1-O-methylquinic acid methyl ester
    3,5-O-Dicaffeoyl-1-O-methylquinic acid methyl ester is a Caffeoylquinic acid derivative. 3,5-O-Dicaffeoyl-1-O-methylquinic acid methyl ester can be isolated from Aster tataricus. 3,5-O-Dicaffeoyl-1-O-methylquinic acid methyl ester does not inhibit LPS-induced nitric oxide production.
    3,5-O-Dicaffeoyl-1-O-methylquinic acid methyl ester
  • HY-N15714
    Acoraminol A
    Acoraminol A is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol B (HY-N15715), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol A has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM).
    Acoraminol A
  • HY-123168
    ZIMET 124/73
    ZIMET 124/73 is a hetarylhydrazone derivative. ZIMET 124/73 is a potent antiviral agent. ZIMET 124/73 can be used for Mengo virus research.
    ZIMET 124/73
  • HY-W050088S
    Isoxepac-d6
    Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088). Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases.
    Isoxepac-d<sub>6</sub>
  • HY-N8064
    Methyl cis-15-tetracosenoate
    		99.9%
    Methyl cis-15-tetracosenoate (Methyl nervonate; Methyl (Z)-tetracos-15-enoate; Nervonic acid methyl ester) is the methyl ester form of nervonic acid (Nervonic acid, HY-N2526). Nervonic acid is an orally active monounsaturated fatty acid. Nervonic acid exerts anti-inflammatory activity by inhibiting the NF-κB signaling pathway. Nervonic acid can be used in the research of neurodegenerative diseases.
    Methyl cis-15-tetracosenoate
  • HY-N10909
    (+)-Epinortrachelogenin
    (+)-Epinortrachelogenin is a natural lignan.
    (+)-Epinortrachelogenin
  • HY-W141863
    DL-Methionine Sulfone
    DL-Methionine Sulfone is a Methionine (HY-13694) derivative.
    DL-Methionine Sulfone