2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3817):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N10909
    (+)-Epinortrachelogenin
    (+)-Epinortrachelogenin is a natural lignan.
    (+)-Epinortrachelogenin
  • HY-W141863
    DL-Methionine Sulfone
    DL-Methionine Sulfone is a Methionine (HY-13694) derivative.
    DL-Methionine Sulfone
  • HY-156879
    Antiproliferative agent-40
    Antiproliferative agent-40 (Compound 9) inhibits proliferation of HT1080 and MCF-7 with IC50s of 52 and 8.2 μM respectively.
    Antiproliferative agent-40
  • HY-N13573
    Adenostemmoic acid D
    Adenostemmoic acid D is a natural diterpene.
    Adenostemmoic acid D
  • HY-120043
    KCO912
    KCO912 is an active compound.
    KCO912
  • HY-N13764
    3,4,5-Trihydroxyallylbenzene 3,4-di-O-glucoside
    3,4,5-Trihydroxyallylbenzene 3,4-di-O-glucoside is a natural phenylacetylene.
    3,4,5-Trihydroxyallylbenzene 3,4-di-O-glucoside
  • HY-107520A
    MNI-caged-L-glutamate TFA
    MNI-caged-L-glutamate TFA is an inert photolabile glutamate precursor. MNI-caged-L-glutamate TFA does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate TFA can be used for research on neurotransmitters.
    MNI-caged-L-glutamate TFA
  • HY-N13820
    Liquiridiolic acid
    Liquiridiolic acid is a natural triterpene.
    Liquiridiolic acid
  • HY-N16728
    Vibralactone K
    Vibralactone K is a natural sesquiterpene.
    Vibralactone K
  • HY-177872
    GQC-05
    GQC-05 (NSC338258), Ellipticine (HY-15753) derivative, is potent and selective c-Myc G-quadruplex ( c-Myc G4) stabilizer with KD values of 0.1-1.43 μM. GQC-05 can reduce Myc expression and induce cancer cells apoptosis. GQC-05 can be used for the research of cancer, such as Burkitt lymphoma.
    GQC-05
  • HY-N13727
    Stephalonine L
    Stephalonine L is a natural alkaloid.
    Stephalonine L
  • HY-118499
    Alpiropride
    Alpiropride (RIV-2093) is a metoclopramide (HY-17382) analog that is effective in reducing the gastrointestinal side effects of cancer chemotherapy drugs. In animal studies, alpiropride showed a stronger antiemetic effect than metoclopramide.
    Alpiropride
  • HY-N17321
    7β-Hydroxystigmasterol
    7β-Hydroxystigmasterol is a natural product that can be found in soybeans.
    7β-Hydroxystigmasterol
  • HY-119860
    Ataprost
    Ataprost (ONO 41483) is an orally active Carboprostacyclin (HY-112322) analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm.
    Ataprost
  • HY-N16749
    trans-Coniferyl acetate
    trans-Coniferyl acetate is a natural phenylacetylene.
    trans-Coniferyl acetate
  • HY-N18295
    Makisterone A 3-acetate
    Makisterone A 3-acetate is a steroid compound found in the Cyanotis arachnoidea.
    Makisterone A 3-acetate
  • HY-119146
    Zolazepam
    Zolazepam (CI-716 free base) is a benzodiazepine derivative with anxiolytic and anticonvulsant properties. Zolazepam combined with Tiletamine causes a decrease in ventilation, resulting in the development of respiratory acidosis. Zolazepam can be used as sedative and muscle relaxants.
    Zolazepam
  • HY-N17320
    Symplocosidin
    Symplocosidin is a natural product that can be found in Symplocos sumuntia?Buch.-Ham. ex D. Don.
    Symplocosidin
  • HY-131603
    Lamivudine triphosphate
    Lamivudine triphosphate (3TCTP) is a phosphorylated Lamivudine (HY-B0250) (a nucleoside analogue). Lamivudine triphosphate inhibits the reverse transcriptase of HIV or HBV viruses to block viral replication by chain termination. Lamivudine triphosphate is also an inhibitor of the RdRp activity of the NS5B subunit of the HCV. Lamivudine triphosphate can be incorporated into the nascent RNA by the SARS-CoV-2 RdRp, thus halting mutations in the nascent SARS-CoV-2 RNA.
    Lamivudine triphosphate
  • HY-N17161
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde is a natural phenolic compound.
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde