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Cat. No.: HY-107520A

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MNI-caged-L-glutamate TFA

Name: MNI-caged-L-glutamate TFA
Brand: MedChemExpress
SKU: HY-107520A
Price: 289.00 USD
Availability: InStock
Rating: 5 (1 reviews)

MNI-caged-L-glutamate TFA is an inert photolabile glutamate precursor. MNI-caged-L-glutamate TFA does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate TFA can be used for research on neurotransmitters.

For research use only. We do not sell to patients.

CAS No.: 2226362-29-2
Formula: C₁₆H₁₈F₃N₃O₈
Molecular Weight:437.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MNI-caged-L-glutamate TFA Chemical Structure

CAS No.: 2226362-29-2

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

MNI-caged L-glutamate (0.1 mM; single 1 ms flashes, repeated up to 8 times) TFA undergoes photolytic conversion with 30-38% efficiency per 1 ms flash in aqueous vesicles^[1].
MNI-caged L-glutamate (250-1000 μM; 5-10 min) TFA does not act as an antagonist at AMPARs in cultured rat hippocampal neurones, and photoreleased L-glutamate activates AMPAR-mediated currents with a half-rise time of 0.78 ms^[1].
MNI-caged L-glutamate (500 μM; 5-10 min) TFA does not act as an antagonist at NMDARs in cultured rat hippocampal neurones^[1].
MNI-caged L-glutamate (1 mM; 5-10 min) TFA does not alter GABA_A R-mediated spontaneous current amplitudes in cultured rat hippocampal neurones^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2226362-29-2
Molecular Weight 437.32
Formula C₁₆H₁₈F₃N₃O₈
SMILES

OC([C@@H](N)CCC(N1C2=C([N+]([O-])=O)C=CC(OC)=C2CC1)=O)=O.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Canepari M, et al. Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters. J Neurosci Methods. 2001 Nov 15;112(1):29-42. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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