MNI-caged-L-glutamate
Based on 1 Customer Validation
MNI-caged-L-glutamate is an inert photolabile glutamate precursor. MNI-caged-L-glutamate does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate can be used for research on neurotransmitters.
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- Pureza: 99.6%
- No. CAS: 295325-62-1
- Fòrmula: C14H17N3O6
- Peso molecular:323.30
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Almacenamiento:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Actividad biológica
MNI-caged L-glutamate (0.1 mM; single 1 ms flashes, repeated up to 8 times) undergoes photolytic conversion with 30-38% efficiency per 1 ms flash in aqueous vesicles[1].
MNI-caged L-glutamate (250-1000 μM; 5-10 min) does not act as an antagonist at AMPARs in cultured rat hippocampal neurones, and photoreleased L-glutamate activates AMPAR-mediated currents with a half-rise time of 0.78 ms[1].
MNI-caged L-glutamate (500 μM; 5-10 min) does not act as an antagonist at NMDARs in cultured rat hippocampal neurones[1].
MNI-caged L-glutamate (1 mM; 5-10 min) does not alter GABAA R-mediated spontaneous current amplitudes in cultured rat hippocampal neurones[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 295325-62-1
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Appearance Solid
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Peso molecular 323.30
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Fòrmula C14H17N3O6
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Color Light yellow to yellow
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SMILES
OC([C@@H](N)CCC(N1C2=C([N+]([O-])=O)C=CC(OC)=C2CC1)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)