Ataprost
Ataprost (ONO 41483) is an orally active Carboprostacyclin (HY-112322) analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 83997-19-7
- 화학식: C21H32O4
- 분자량:348.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
Platelet aggregation[1]
In Vitro
Ataprost inhibits platelet aggregation in human and baboon platelet rich plasma (PRP) with ED50s of 1.91 ng/mL and 4.38 ng/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
Ataprost (i.v.; single dose) inhibits platelet aggregation with an ED50 value of 3.2 μg/kg in baboon[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 83997-19-7
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분자량 348.48
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화학식 C21H32O4
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SMILES
O[C@@H](C1CCCC1)/C=C/[C@@H]2[C@](C/3)([H])[C@](CC3=C/CCCC(O)=O)([H])C[C@H]2O
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Synonyms
ONO 41483
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)