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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Verwandte Produkte (3822):

Art. -Nr. Produktname Wirkung Reinheit Chemical Structure
  • HY-159093
    Antitumor agent-178
    Antitumor agent-178 (compound 4 h) is a potent and selective GSCs inhibitor. Antitumor agent-178 has the potential for the research of cancer.
    Antitumor agent-178
  • HY-176994
    3-Et-3TC
    3-Et-3TC (Page 87, Compound 3b) is a structurally modified derivative of Lamivudine (HY-B0250). 3-Et-3TC can inhibit the activation of the NLRP3 inflammasome and can be used for the study of retinal degenerative diseases.
    3-Et-3TC
  • HY-49457
    Copper(II) ionophore I
    Copper(II) ionophore I is a neutral Cu+ ionophore.
    Copper(II) ionophore I
  • HY-N7482
    Pyranocoumarin
    Pyranocoumarin (Compound 13) is a heterocyclic scaffold (coumarin + pyran ring fusion). Pyranocoumarin inhibits the S-warfarin hydroxylation catalyzed by CYP2C9.
    Pyranocoumarin
  • HY-183712
    Antibacterial agent 345
    Antibacterial agent 345 is a Ciprofloxacin (HY-B0356)-lipophilic derivative and is an antibacterial agent. Antibacterial agent 345 inhibits DNA gyrase and inhibits bacterial DNA replication and transcription. Antibacterial agent 345 inhibits bacterial biofilm formation. Antibacterial agent 345 can be used for the research of bacterial infections, such as Pseudomonas aeruginosa infection.
    Antibacterial agent 345
  • HY-N13030
    Bisacurone B
    Bisacurone B is a natural sesquiterpene.
    Bisacurone B
  • HY-W715084
    2-CEC hydrochloride
    		Control
    2-CEC hydrochloride is structurally categorized as a drug derivative.
    2-CEC hydrochloride
  • HY-176012
    1S-LSD
    1S-LSD (1S-Lysergic acid diethylamide; 1S-LAD) is a lysergic acid diethylamide analog and is a psychoactive substance.
    1S-LSD
  • HY-N7818
    3-(Methylthio)propyl acetate
    3-(Methylthio)propyl acetate is a heavy volatile sulfur compound with mushroom, onion, garlic odour. 3-(Methylthio)propyl acetate can be found in Vinhos Verdes wines. 3-(Methylthio)propyl acetate occurs in high content in Trajadura wines and low content in Azal Branco wines.
    3-(Methylthio)propyl acetate
  • HY-19597
    BASF 43915
    BASF 43915 (Pelretin) is a Phenyl analog.
    BASF 43915
  • HY-B1045
    Chlorazanil hydrochloride
    Chlorazanil hydrochloride is an orally effective diuretic.
    Chlorazanil hydrochloride
  • HY-W750672
    Astaxanthin dipalmitate
    Astaxanthin dipalmitate is a carotenoid. Astaxanthin dipalmitate can be used for pigmentation of rainbow trout and sea trout. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition.
    Astaxanthin dipalmitate
  • HY-180767
    Azithromycin-amide-C3-amide-quinoxaline
    Azithromycin-amide-C3-amide-quinoxaline (Compound 5f) is an Azithromycin (HY-17506) derivative and antibacterial agent. Azithromycin-amide-C3-amide-quinoxaline inhibits topoisoisomerase I with an IC50 of 120.7 μM. Azithromycin-amide-C3-amide-quinoxaline interacts with 70S E. coli ribosome with a Kd of 0.8 nM. Azithromycin-amide-C3-amide-quinoxaline inhibits bacterial translation with an IC50 of 0.7 μM. Azithromycin-amide-C3-amide-quinoxaline shows antibacterial potency against S. pneumonia ATCC 49619, S. aureus ATCC 29213, E. faecalis ATCC 29212 with MICs of 0.06 μg/mL, 2 μg/mL, 0.5 μg/mL, respectively. Azithromycin-amide-C3-amide-quinoxaline exhibits anticancer activity against prostate cancer, colon cancer.
    Azithromycin-amide-C3-amide-quinoxaline
  • HY-W102525
    Rose oxide
    Rose oxide is a kind of monoterpenoid volatile organic compound with a distinctive rose fragrance. However, rose oxide does not have inhibitory activity against the formation of breast cancer stem cells.
    Rose oxide
  • HY-172751
    1(R)-Tetrahydrocannabidiol
    1(R)-Tetrahydrocannabidiol (Compound 4) is a drug derivative that can be used in research on neurological diseases.
    1(R)-Tetrahydrocannabidiol
  • HY-139352
    Betamethasone 21-valerate
    		98.0%
    Betamethasone 21-valerate is a corticosteroid ester with anti-inflammatory activities.
    Betamethasone 21-valerate
  • HY-183226
    Heparin disaccharide II-A disodium
    Heparin disaccharide II-A disodium is a derivative of Heparin (HY-17567) and can be used for modifying nanoparticles.
    Heparin disaccharide II-A disodium
  • HY-175112
    8-(2-Azidobenzylthio) NAD+ sodium
    8-(2-Azidobenzylthio) NAD+ (sodium) is a clickable form of the signaling molecule and enzyme cofactor NAD+.
    8-(2-Azidobenzylthio) NAD+ sodium
  • HY-W281950
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride is a thiourea compound and an Isothiourea derivative, with potential antidiabetic activity.
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride
  • HY-N15564
    Theleganbanin B
    Theleganbanin B is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin B inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin B inhibits the phosphorylation of JAK2/STAT3. Theleganbanin B is promising for research of neurodegenerative diseases .
    Theleganbanin B