2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W267524
    H-Phe(3-CF3)-OH
    H-Phe (3-CF3)-OH is a phenylalanine derivative targeting the L-type amino acid transporter 1 (LAT1, SLC7A5) as its core target, and it belongs to LAT1 substrates. H-Phe (3-CF3)-OH can be used for prodrug scaffold development and research related to multiple solid tumors.
    H-Phe(3-CF3)-OH
  • HY-116185
    N-Acetyl-3,4-MDMC
    		99.9%
    N-Acetyl-3,4-methylenedioxymethcathinone is structurally categorized as a drug derivative.
    N-Acetyl-3,4-MDMC
  • HY-124479A
    γ-Lumicolchicine
    		99.70%
    γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569) that can be used as an experimental control for Colchicine action.
    γ-Lumicolchicine
  • HY-W049311
    4-Methyl-5,6,7,8-tetrahydroquinoline
    		99.80%
    4-Methyl-5,6,7,8-tetrahydroquinoline, a tetrahydroquinoline alkaloid, is isolated from the roots of Glycyrrhiza uralensis Fisch.
    4-Methyl-5,6,7,8-tetrahydroquinoline
  • HY-75279
    N-Acetyl-β-neuraminic acid methyl ester
    		98.0%
    N-Acetyl-β-neuraminic acid methyl ester (N-Acetyl-Neuraminic acid (Sialic acid)) is an ester compound.
    N-Acetyl-β-neuraminic acid methyl ester
  • HY-W585819
    3-Chloropropane-1,2-diol dipalmitate
    3-Chloropropane-1,2-diol dipalmitate (3-MPCD dipalmitate) is a fatty acid ester of 3-monochloropropane-1,2-diol (3-MCPD) and a foodborne contaminant.
    3-Chloropropane-1,2-diol dipalmitate
  • HY-153823
    UDP-6N3Gal
    UDP-6N3Gal, a derivative UDP-Galactose (HY-150524), is a 6-azido-modified uridine diphosphate galactose. UDP-6N3Gal can label cell surface glycoproteins and can be used in the research of glycosylation imaging.
    UDP-6N3Gal
  • HY-403658
    IOX2-NH2
    IOX2-NH2 (example 115) is a derivative of IOX2 (HY-15468). IOX2 is a chemical probe, and a specific prolyl hydroxylase-2 (PHD2) inhibitor.
    IOX2-NH2
  • HY-166313
    Docosanoyl-L-carnitine hydrochloride
    		99.79%
    Docosanoyl-L-carnitine (hydrochloride) is an ester product.
    Docosanoyl-L-carnitine hydrochloride
  • HY-W613967
    Hexacosanedioicacid
    		99.93%
    Hexacosanedioicacid is an ester product.
    Hexacosanedioicacid
  • HY-W046317
    CBIO
    		99.85%
    CBIO (Compound 4e) is a 1,2-Benzisoxazole (HY-W103317) derivative.
    CBIO
  • HY-402853
    3-(Tritylthio)propylamine
    3-(Tritylthio)propylamine (Compound 32) is a methyl-containing analogue of S-Trityl-L-cysteine (HY-W011102).
    3-(Tritylthio)propylamine
  • HY-114649
    19-Hydroxy cholesterol
    		≥99.0%
    19-Hydroxy cholesterol is an ester product.
    19-Hydroxy cholesterol
  • HY-N11229
    Butyl caffeate
    		98.15%
    Butyl caffeate (Caffeic acid butyl ester) is a caffeic acid derivative with antioxidant activity and lipophilicity (DPPH IC50 = 14.1 μM). Butyl caffeate protects neuronal PC12 cells against oxidative stress. Butyl caffeate can be used for oxidative stress related and neurodegenerative diseases research.
    Butyl caffeate
  • HY-13987
    (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid
    		98.45%
    (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid is a Phe analog.
    (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid
  • HY-W100491
    Trimethylbenzoquinone
    		99.87%
    Trimethylbenzoquinone (Compound 5) is a methylated benzoquinone. Trimethylbenzoquinone exhibits moderate cytotoxicity against K562 cells, with its IC50 being 0.75 μM. Trimethylbenzoquinone is completely unable to cause inter-strand DNA cross-linking and cannot alkylate DNA guanines. Trimethylbenzoquinone can be used to study the relationship between the nitrogen heterocyclic group and DNA cross-linking.
    Trimethylbenzoquinone
  • HY-N16226
    13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid
    13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid is a fatty acid.
    13-Hydroxy-12-oxo-9(Z),15(Z)-octadecadienoic acid
  • HY-113468AR
    3-O-Methyldopa (Standard)
    3-O-Methyldopa (Standard) is the analytical standard of 3-O-Methyldopa. This product is intended for research and analytical applications. 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.
    3-O-Methyldopa (Standard)
  • HY-124282
    17-Hydroxyheptadecanoic acid
    		99.70%
    17-Hydroxyheptadecanoic acid (ω-Hydroxyheptadecanoic acid) is an ester product.
    17-Hydroxyheptadecanoic acid
  • HY-101595
    RPH-2823
    		≥99.0%
    RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance.
    RPH-2823