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  4. RPH-2823

RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance.

For research use only. We do not sell to patients.

RPH-2823 Chemical Structure

RPH-2823 Chemical Structure

CAS No. : 96558-24-6

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RPH-2823 Related Antibodies

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Description

RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance[1].

In Vitro

RPH-2823 influences transepithelial Na+ transport by interacting with the Na+ channel or a regulator site of it within the apical membrane[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RPH-2823 Related Antibodies
In Vivo

RPH 2823 (2.5 mumol/kg) can avoid the kaliuresis of 25 mumol/kg furosemide in male Wistar rats. RPH 2823 (1 mg/kg and 5 mg/kg, i.v.) has a terminal elimination half-life of 3 h. About 47% of the given dose are excreted unchanged with urine[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

370.41

Formula

C17H22N8O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(COC1=CC=C(C2=NC3=C(N)N=C(N)N=C3N=C2N)C=C1)CN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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RPH-2823 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RPH-282396558-24-6RPH2823RPH 2823OthersInhibitorinhibitorinhibit

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HY-101595
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