H-Phe(3-CF3)-OH
Based on 1 Customer Validation
H-Phe (3-CF3)-OH is a phenylalanine derivative targeting the L-type amino acid transporter 1 (LAT1, SLC7A5) as its core target, and it belongs to LAT1 substrates. H-Phe (3-CF3)-OH can be used for prodrug scaffold development and research related to multiple solid tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 14464-68-7
- 分子式: C10H10F3NO2
- 分子量:233.19
-
保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
体外実験
H-Phe (3-CF3)-OH (Compound 66) acts as a substrate of human LAT1 in induced TREx HEK-hLAT1 cells, with a relative exchange efflux rate of 59% vs L-phenylalanine, and inhibits [3H]-gabapentin uptake by 87% at 200 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
-
CAS 番号 14464-68-7
-
性状 Solid
-
分子量 233.19
-
分子式 C10H10F3NO2
-
SMILES
C([C@@H](C(O)=O)N)C1=CC(C(F)(F)F)=CC=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)