2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W420336
    Fluopicolide
    		99.43%
    Fluopicolide is the active compound.
    Fluopicolide
  • HY-W017093
    3,5-Dimethoxybenzyl alcohol
    		99.90%
    3,5-Dimethoxybenzyl alcohol is a Phenols product that can be isolated from the herbs of Pinus sylvestris.
    3,5-Dimethoxybenzyl alcohol
  • HY-34781
    4'-Trifluoromethyl-2-biphenyl carboxylic acid
    		99.91%
    4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent.
    4'-Trifluoromethyl-2-biphenyl carboxylic acid
  • HY-W017355
    4-Hydroxythiobenzamide
    4-Hydroxythiobenzamide (4-Hydroxybenzothioamide) (Compound HT), a benzothiazole derivative of Nootkatone (HY-N2195), serves as an intermediate.
    4-Hydroxythiobenzamide
  • HY-N16228
    16-Oxo-octadecanoic acid
    		99.80%
    16-Oxo-octadecanoic acid is an octadecanoid.
    16-Oxo-octadecanoic acid
  • HY-168400
    3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride
    		99.9%
    3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is structurally categorized as a drug derivative.
    3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride
  • HY-168829
    4-Methylphenmetrazine hydrochloride
    		99.40%
    4-Methylphenmetrazine hydrochloride is a phenmetrazine.
    4-Methylphenmetrazine hydrochloride
  • HY-W087207
    Loxoprofen L-menthol ester
    		99.73%
    Loxoprofen L-menthol ester is a degradation product Loxoprofen sodium (HY-B0578A). Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties.
    Loxoprofen L-menthol ester
  • HY-W800826
    2-Oleoyl-3-chloropropanediol
    2-Oleoyl-3-chloropropanediol is an ester product.
    2-Oleoyl-3-chloropropanediol
  • HY-161088
    Anti-aging agent 1
    		98.75%
    Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL.
    Anti-aging agent 1
  • HY-178054
    LMDP10
    		99.91%
    LMDP10 is an orally active 3-amino quinazoline derivative with Keap1-Nrf2 pathway activation activity. LMDP10 binds to Keap1 to inhibit Keap1-Nrf2 interaction, thereby activating the Nrf2 pathway. LMDP10 elevates Nrf2, SOD, and GSH levels, reduces MDA and TNF-α levels, attenuates neurodegeneration, and improves memory function in Alzheimer’s disease (AD) rats. LMDP10 can be used for the study of AD.
    LMDP10
  • HY-114231C
    Exaluren sulfate
    Exaluren (ELX-02; NB-124) sulfate is an synthetic eukaryotic ribosome-selective glycoside that induces read-through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren sulfate is used for the research of cystic fibrosis caused by nonsense mutations.
    Exaluren sulfate
  • HY-101965
    SPI-112Me
    SPI-112Me is an active compound.
    SPI-112Me
  • HY-145554
    Bafrekalant
    		99.67%
    Bafrekalant is a diazabicyclic substituted imidazo[l,2-a]pyrimidine-derivative. Bafrekalant has the potential for the research of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring (extracted from patent WO2018228907A1).
    Bafrekalant
  • HY-B1714
    NSC 601980 analog
    		98.0%
    NSC 601980 analog is an analogue of NSC601980. In yeast screening experiments, NSC 601980 exhibited antitumor activity, effectively inhibiting cell proliferation in both COLO 205 and HT29 cell lines, with Log GI 50 values of -6.6 and -6.9, respectively.
    NSC 601980 analog
  • HY-76665
    Anticancer agent 209
    		≥99.0%
    Anticancer agent 209 (compound 1) is an anticancer agent. Anticancer agent 209 exhibits cytotoxic activity against colon cancer in vitro.
    Anticancer agent 209
  • HY-W000701
    Isourolithin A
    		98.08%
    Isourolithin A (Iso-uroA) is a flavonoid compound. Isourolithin A is applicable to anti-inflammatory and antioxidant research.
    Isourolithin A
  • HY-34887
    Acridone-4-carboxylic acid
    		98.69%
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM.
    Acridone-4-carboxylic acid
  • HY-W051530
    8-Methoxyquinoline

    8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer.
    8-Methoxyquinoline
  • HY-101556
    Namirotene
    		99.33%
    Namirotene (CBS-211A) is a retinoic acid analog, which is utilized in topical eye administration. Namirotene enhances 1α,25-dihydroxyvitamin D3-induced cytotoxicity in cell U937 and induces the differentation in U937.
    Namirotene