4'-Trifluoromethyl-2-biphenyl carboxylic acid

Cat. No.: HY-34781 Purity: 99.91%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent.

For research use only. We do not sell to patients.

4'-Trifluoromethyl-2-biphenyl carboxylic acid Chemical Structure

CAS No. : 84392-17-6

Size	Price	Stock	Quantity
100 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent^[1].

In Vivo

4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Diet-induced hypercholesterolemic African green monkeys^[5]
Dosage:	15-60 mg/kg
Administration:	Oral administration (p.o.)
Result:	Reduced serum LDL-cholesterol concentrations.

Molecular Weight

266.22

Formula

C₁₄H₉F₃O₂

CAS No.

84392-17-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : ≥ 250 mg/mL (939.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7563 mL	18.7815 mL	37.5629 mL
5 mM	0.7513 mL	3.7563 mL	7.5126 mL
10 mM	0.3756 mL	1.8781 mL	3.7563 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.91%

Select Batch:

Data Sheet (273 KB) SDS (0 KB)

COA (251 KB) LCMS (280 KB)

Handling Instructions (2659 KB)

References

[1]. Lewis MC, et al. Evaluation of the hypolipidemic activity of xenalipin in experimental animals. Atherosclerosis. 1987 Mar;64(1):27-35. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7563 mL	18.7815 mL	37.5629 mL	93.9073 mL
	5 mM	0.7513 mL	3.7563 mL	7.5126 mL	18.7815 mL
	10 mM	0.3756 mL	1.8781 mL	3.7563 mL	9.3907 mL
	15 mM	0.2504 mL	1.2521 mL	2.5042 mL	6.2605 mL
	20 mM	0.1878 mL	0.9391 mL	1.8781 mL	4.6954 mL
	25 mM	0.1503 mL	0.7513 mL	1.5025 mL	3.7563 mL
	30 mM	0.1252 mL	0.6260 mL	1.2521 mL	3.1302 mL
	40 mM	0.0939 mL	0.4695 mL	0.9391 mL	2.3477 mL
	50 mM	0.0751 mL	0.3756 mL	0.7513 mL	1.8781 mL
	60 mM	0.0626 mL	0.3130 mL	0.6260 mL	1.5651 mL
	80 mM	0.0470 mL	0.2348 mL	0.4695 mL	1.1738 mL
	100 mM	0.0376 mL	0.1878 mL	0.3756 mL	0.9391 mL