8-Methoxyquinoline
Based on 1 Customer Validation
8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 938-33-0
- Formula: C10H9NO
- Molecular Weight:159.18
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer[1].
8-Methoxyquinoline (10 μM; 1-2 h) does not facilitate copper transport into DCIS cells when mixed with CuCl2[1].
8-Methoxyquinoline-CuCl2 mixtures (1.0-20.0 μM; 24 h) has much less growth-
inhibitory effect in contrast to that of 8-hydroxyquinoline-CuCl2 in DCIS cells[1].
8-Methoxyquinoline-CuCl2 mixtures (1.0-5.0 μM; 8-12 h) do not inhibit proteasomal CT-like activity in DCIS cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 938-33-0
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Appearance Solid
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Molecular Weight 159.18
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Formula C10H9NO
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SMILES
COC1=CC=CC2=C1N=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)