Anti-aging agent 1
Based on 1 Customer Validation
Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL.
For research use only. We do not sell to patients.
- Purity: 98.75%
- CAS No.: 1884611-28-2
- Formula: C16H16ClNO3
- Molecular Weight:305.76
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| WI-38 | IC50 |
0.16 μM
Compound: 24
|
Senolytic activity in ionizing radiation induced human WI-38 senescent cells by PI staining based flow cytometry analysis
Senolytic activity in ionizing radiation induced human WI-38 senescent cells by PI staining based flow cytometry analysis
|
[PMID: 38104906] |
| WI-38 | IC50 |
1.5 μM
Compound: 24
|
Senolytic activity in non-senescent human WI-38 cells by PI staining based flow cytometry analysis
Senolytic activity in non-senescent human WI-38 cells by PI staining based flow cytometry analysis
|
[PMID: 38104906] |
Chemical Information
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CAS No. 1884611-28-2
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Appearance Solid
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Molecular Weight 305.76
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Formula C16H16ClNO3
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Color White to off-white
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SMILES
COC1=CC=C(/C=C/C(N2CCCC=C(Cl)C2=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)