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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-124245
    3-Hydroxy desloratadine
    3-Hydroxy desloratidine is a metabolite of Desloratidine.
    3-Hydroxy desloratadine
  • HY-116167
    RY 024
    RY 024 is an active compound.
    RY 024
  • HY-N16975
    (1R,2S)-Guaiacylglycerol β-coniferyl ether
    (1R,2S)-Guaiacylglycerol β-coniferyl ether is a natural lignan.
    (1R,2S)-Guaiacylglycerol β-coniferyl ether
  • HY-N2739
    7,4'-Di-O-methylapigenin 5-O-glucoside
    7,4'-Di-O-methylapigenin 5-O-glucoside is a natural flavonoid.
    7,4'-Di-O-methylapigenin 5-O-glucoside
  • HY-137933
    5,6,7-Trimethoxycoumarin
    5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea.
    5,6,7-Trimethoxycoumarin
  • HY-N17878
    Guavinoside A
    Guavinoside A is a benzophenone galloyl glycoside found in the leaves of Psidium guajava L..
    Guavinoside A
  • HY-N16976
    6β-Ethoxy-8β,10β- dihydroxyeremophil-7(11)-en-12,8α-olide
    6β-Ethoxy-8β,10β- dihydroxyeremophil-7(11)-en-12,8α-olide is a natural sesquiterpene.
    6β-Ethoxy-8β,10β- dihydroxyeremophil-7(11)-en-12,8α-olide
  • HY-W750681
    (13Z)-Canthaxanthin
    (13Z)-Canthaxanthin (13-cis-Canthaxanthin) is a carotenoid that exists in salmon feds. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition.
    (13Z)-Canthaxanthin
  • HY-18005
    4-Aza-Oleanolic acid methyl ester
    4-Aza-Oleanolic acid methyl ester is a triterpenic derivative.
    4-Aza-Oleanolic acid methyl ester
  • HY-N17978
    Ecliptasaponin B
    Ecliptasaponin B (compound 7) is a triterpenoid saponin and growth inhibitor present in the leaves of Aralia elata Seem.
    Ecliptasaponin B
  • HY-106622
    TEI-6122
    TEI-6122 is a 7-thiaprostaglandin E1 derivative. TEI-6122 can reduce urinary protein and suppressthe increase of blood urea nitrogen. TEI-6122 can inhibit monocyte chemoattractant protein-1 induced chemotaxis. TEI-6122 can be used for the research of inflammation, such as nephritis.
    TEI-6122
  • HY-106317
    Glutathione monoisopropyl ester
    Glutathione monoisopropyl ester (Glutathione isopropyl ester) is an ester derivative of glutathione. Glutathione monoisopropyl ester can increase glutathione concentrations in tissues such as the liver, lungs, heart, and brain of mice, exerting a dose-dependent protective effect against liver injury. Glutathione monoisopropyl ester effectively inhibits ultraviolet-induced lipid peroxidation, inflammatory responses, and tumorigenesis in the skin of hairless mice by maintaining epidermal glutathione levels. Glutathione monoisopropyl ester also inhibits the progression of X-ray-induced cataracts in rats.
    Glutathione monoisopropyl ester
  • HY-165624
    LY-41
    LY-41 is a 2-aminotetralin (HY-W022362) derivative related to 8-OH-DPAT (HY-112061). LY-41 decreases 5-HT synthesis. LY-41 induces 5-HT motor syndrome. (R)-LY-41 and (S)-LY-41 are novel 5-HT1A receptor agonists.
    LY-41
  • HY-N17350
    Praeruptorin H
    Praeruptorin H is a natural product that can be found in white flower peucedanum.
    Praeruptorin H
  • HY-W712539
    Homodihydrocapsaicin II
    Homodihydrocapsaicin II is a capsaicinoid with analgesic and anti-inflammatory effects, which is found in capsicum fruits. Homodihydrocapsaicin II is promising for research of inflammatory diseases and neuropathic pain.
    Homodihydrocapsaicin II
  • HY-107120
    CB-182804
    CB-182804, Polymyxin B (HY-149179) analogue, is a polypeptide antibiotic. CB-182804 has inhibitory activity against all Gram-negative pathogenic bacteria, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa with MIC50 values of 2 μg/mL. CB-182804 is mainly used for the research on refractory infections caused by multidrug-resistant (MDR) Gram-negative bacteria.
    CB-182804
  • HY-N18014
    Naringenin 4',7-dimethyl ether
    Naringenin 4',7-dimethyl ether, Naringenin (HY-N0100) derivative is an anti-seizure agent. Naringenin 4',7-dimethyl ether attenuates pentylenetetrazole-induced seizures in larval zebrafish and reduces seizures in the mouse 6-Hz psychomotor seizure model. Naringenin 4',7-dimethyl ether can be used for the research of epilepsy.
    Naringenin 4',7-dimethyl ether
  • HY-N17169
    Physcion-10,10'-bianthrone
    Physcion-10,10'-bianthrone is a natural anthraquinone.
    Physcion-10,10'-bianthrone
  • HY-106166
    α-Epibromide
    α-Epibromide (16α-Bromoepiandrosterone) is an adrenal steroid derivative. α-Epibromide decreases nitric oxide production. α-Epibromide restores T helper cell type 1 activity and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis. α-Epibromide reduces mortality related to excessive inflammation and opportunistic lung infections.
    α-Epibromide
  • HY-W659059
    N-Methyl-1-phenylpropan-1-amine hydrochloride
    N-Methyl-1-phenylpropan-1-amine hydrochloride is structurally categorized as a benzylamine.
    N-Methyl-1-phenylpropan-1-amine hydrochloride