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Cat. No.: HY-137933

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5,6,7-Trimethoxycoumarin

5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea.

For research use only. We do not sell to patients.

CAS No.: 55085-47-7
Formula: C₁₂H₁₂O₅
Molecular Weight:236.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

5,6,7-Trimethoxycoumarin Chemical Structure

CAS No.: 55085-47-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>50 μM Compound: 28	Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay	[PMID: 33939429]
U-937	CC₅₀	0.79 mM Compound: BA-7	Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay	[PMID: 19716307]
U-937	IC₅₀	182.1 μM Compound: BA-7	Growth inhibition of human U937 cells assessed as [3H]5-methyl thymidine incorporation after 48 hrs by liquid scintillation counting Growth inhibition of human U937 cells assessed as [3H]5-methyl thymidine incorporation after 48 hrs by liquid scintillation counting	[PMID: 19716307]

Chemical Information

CAS No. 55085-47-7
Molecular Weight 236.22
Formula C₁₂H₁₂O₅
SMILES

O=C1C=CC2=C(OC)C(OC)=C(OC)C=C2O1
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee SJ, et al. Artemisterol, a new steryl ester from the whole plant of Artemisia apiacea. J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):313-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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