Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4630)
Related Products (4630)
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4-Tolyl-sulfonamide-d4
0 ImagesCat. No.: HY-79602SCAS No.: 1219795-34-2Synonyms: p-Tosylamide-d44-Tolyl-d4-sulfonamide (p-Tosylamide-d4) is the d4-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research.
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Doxepin-d3
0 ImagesCat. No.: HY-139521SCAS No.: 138387-16-3Doxepin-d3 is the deuterated-labeled Doxepin (HY-B0725A). Doxepin is an orally active, blood-brain barrier penetrant tricyclic antidepressant with multiple activities including hypnosis, sedation, analgesia and vasodilation. Doxepin enhances the expression of PSD-95 and synapsin 1 via the PI3K/AKT/mTOR signaling pathway, and is metabolized to Desmethyldoxepin in vivo. Doxepin can be used in research related to various diseases such as depression, anxiety, obesity and atopic dermatitis.
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5-Ethoxy-4-methyloxazole
0 ImagesCat. No.: HY-W006448CAS No.: 5006-20-25-Ethoxy-4-methyloxazole
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3,3-Dimethylcyclohexanol
0 ImagesCat. No.: HY-W559929CAS No.: 767-12-43,3-Dimethylcyclohexanol is a major odor-active compound. 3,3-Dimethylcyclohexanol can be isolated from the volatile extracts of Mayapan and Jaguar.
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NRMA-6
0 ImagesCat. No.: HY-164508CAS No.: 2375659-13-3NRMA-6, an amide prodrug, is a nuclear receptor modulator.
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(Z)-3-Hexenal
0 ImagesCat. No.: HY-W747972ACAS No.: 6789-80-6(Z)-3-Hexenal is an isomer of Hydrosorbaldehyde (HY-W747972). (Z)-3-Hexenal is a green leaf volatile and also the main contributor to the fresh, grassy aroma of tea leaves. (Z)-3-Hexenal undergoes irreversible conversion to (E)-2-hexenal via (Z)-3:(E)-2-hexenal isomerase (CsHI). (Z)-3-Hexenal plays a key role in protecting plants against biotic stresses (such as pathogens and insects) and acting as a signaling chemical.
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tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate
![tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate](https://file.medchemexpress.com/product_pic/hy-135208.gif "Click to View tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate Product Detail")
0 ImagesCat. No.: HY-135208CAS No.: 916048-02-7tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound.
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7-Ketologanic acid
0 ImagesCat. No.: HY-N17690CAS No.: 170382-11-37-Ketologanic acid is an iridoid glucoside. 7-Ketologanic acid is an efficient precursor for 8-epi-kingisidic acid. 7-Ketologanic acid can be extracted from dry leaves of P. azorica.
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Erythromycin F
0 ImagesCat. No.: HY-Z8234CAS No.: 82230-93-1Erythromycin F is one of the components of Erythromycin (HY-B0220), in which Erythromycin is a cyclic lactone antibiotic.
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Dimethyl adipate-d4
0 ImagesCat. No.: HY-W015301SCAS No.: 76785-05-2Synonyms: Hexanedioic acid dimethyl ester-d4Dimethyl adipate-d4 (Hexanedioic acid dimethyl ester-d4) is the deuterium labeled Dimethyl adipate (HY-W015301). Dimethyl adipate is an aliphatic dicarboxylate compound. Dimethyl adipate is mainly used as a plasticizer and an intermediate in organic synthesis.
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MC-Gly-Gly-Phe-Exatecan analog 38
0 ImagesCat. No.: HY-178290CAS No.: 2766214-01-9MC-Gly-Gly-Phe-Exatecan analog 38 (Compound L-II-4) is part of an antibody-drug conjugate (ADC), consisting of an ADC toxicant molecule and an ADC linker. MC-Gly-Gly-Phe-Exatecan analog 38 can be used to synthesize ADCs (such as ADC-II-15 and ADC-III-13). MC-Gly-Gly-Phe-Exatecan analog 38 can also be used in cancer research (ADC Cytotoxin: HY-178315, ADC Linker: HY-44235).
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Calcium 4-oxopentanoate
0 ImagesCat. No.: HY-W129199CAS No.: 591-64-0Synonyms: Calcium levulinateCalcium 4-Oxopentanoate (levulinic acid calcium) is an effective oral calcium supplement and is commonly used as a food additive. Calcium 4-Oxopentanoate can be reduced in the liver to 4-hydroxypentanoate (HY-W107263), and ethanol enhances this reduction process. Calcium 4-Oxopentanoate can be used for studies on calcium deficiency.
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Furfuryl acetate (Standard)
0 ImagesTetracaine (Standard) is the analytical standard of Tetracaine. This product is intended for research and analytical applications. 0
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Stemmadenine
0 ImagesCat. No.: HY-N19310CAS No.: 10012-73-4Stemmadenine is a strychnos-type monoterpenoid indole alkaloid that serves as a biosynthetic precursor of the monoterpenoid indole alkaloid skeleton.
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4-Methylethylbenzene
0 Images4-Methylethylbenzene is a volatile aromatic hydrocarbon compound. 4-Methylethylbenzene can be isolated from the essential oil of the peels of Juglans nigra L. .
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NRMA-I
0 ImagesCat. No.: HY-164512CAS No.: 1417653-47-4NRMA-I is the amide produrg of the small molecule nuclear receptor modulator. NRMA-I exhibits a higher exposure in the brain, indicating that a good blood-brain barrier (BBB) penetration. NRMA-I can be used for research of central nervous system diseases related to nuclear receptors, such as Alzheimer's disease and Parkinson's disease.
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Octadecanedioic acid (Standard)
0 ImagesOctadecanedioic acid (Standard) is an analytical standard of Octadecanedioic acid (HY-W005178). This product is intended for research and analytical applications. Octadecanedioic acid is an aliphatic dibasic acid and also serves as a comonomer unit for biodegradable oligo (ester amide).
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XL388-C2-amide-PEG9-NH2 hydrochloride
0 ImagesCat. No.: HY-139085AXL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog.
