Quazolast
Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.
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- CAS No.: 86048-40-0
- 화학식: C12H7ClN2O3
- 분자량:262.65
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:150 g Male Sprague Dawley rat[1]
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Dosage:0.2, 1, 5 mg/kg
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Administration:P.o.
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Result:Decreased the rat gastric mucosa damage in a dose dependent manner and reduced the gastric ulcer index (68%) at 5 mg/kg in rat induced by absolute ethanol (0.9 mg/kg).
Chemical Information
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CAS No. 86048-40-0
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분자량 262.65
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화학식 C12H7ClN2O3
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SMILES
COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O
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Synonyms
RHC 3988
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. [Content Brief]
[2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Quazolast Related Classifications
HY-106083 Related Classifications
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