86048-40-0
86048-40-0
Chemical Structure
Quazolast
Synonym(s): RHC 3988
- CAS No.: 86048-40-0
- Formula:C12H7ClN2O3
- Molecular Weight:262.65
IUPAC Name: methyl 5-chlorooxazolo[4,5-h]quinoline-2-carboxylate
InChIKey: ZCRBUWNCWCWRGL-UHFFFAOYSA-N
SMILES: COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O
Biological Activity: Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers[1][2].
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Quazolast | Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers. | |||||||||||||||||||||
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References
- [1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6. [Content Brief]
- [2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302. [Content Brief]
Keywords
