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Cat. No.: HY-183082

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Mal-GFLG-TPP-PPA

Mal-GFLG-TPP-PPA is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs. Mal-GFLG-TPP-PPA is used in the synthesis of PEG-iPDPA-GFLG-Y-TPPa.

For research use only. We do not sell to patients.

Formula: C₈₈H₉₃BrN₁₁O₁₁P
Molecular Weight:1591.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mal-GFLG-TPP-PPA Chemical Structure

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Biological Activity

Description

Mal-GFLG-TPP-PPA is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs. Mal-GFLG-TPP-PPA is used in the synthesis of PEG-iPDPA-GFLG-Y-TPPa^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

Molecular Weight 1591.62
Formula C₈₈H₉₃BrN₁₁O₁₁P
SMILES

O=C(CNC(CCN1C(C=CC1=O)=O)=O)N[C@H](C(N[C@H](C(NCC(OC2=CC=C(C=C2)CC(C(NCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)NC(CC[C@H](/C(N/6)=C7\CC8=O)[C@@H](C6=C\C(C(C)=C/9C=C)=NC9=C/C%10=C(C(CC)=C(/C=C%11N=C7C8=C\%11C)N%10)C)C)=O)=O)=O)CC(C)C)=O)CC%12=CC=CC=C%12.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liu J, et al. Lysosome-Mitochondria Cascade Targeting Nanoparticle Drives Robust Pyroptosis for Cancer Immunotherapy. J Am Chem Soc. 2024 Dec 18;146(50):34568-34582. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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