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Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Productos relacionados con Drug Isomer (434):

Cat. No. Nombre del producto Efecto Pureza Chemical Structure
  • HY-129133
    cis-Miyabenol C
    cis-Miyabenol C is an isomer of the resveratrol trimer Miyabenol C, which can be isolated from grape herbs. Miyabenol C is an inhibitor of β-amyloid (Aβ) and amyloid β precursor protein (APP) in Alzheimer's disease model mice, and inhibit β-secretase activity without changing the protein level of β-secretase BACE1.
    cis-Miyabenol C
  • HY-W747129
    15(R)-Prostaglandin I2 sodium
    15(R)-Prostaglandin I2 (15(R)-PGI2) sodium is a 15(R)-stereoisomer of Epoprostenol (Prostaglandin I2) sodium (HY-A0126A).
    15(R)-Prostaglandin I2 sodium
  • HY-141176B
    cis-Cyclooctene-amine
    cis-Cyclooctene-amine is the cis isomer of TCO-amine (HY-141176). TCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-amine is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    cis-Cyclooctene-amine
  • HY-145530
    (S)-Hydroxychloroquine sulfate
    (S)-Hydroxychloroquine ((S)-HCQ) sulfate is an isomer of Hydroxychloroquine (HY-W031727). (S)-Hydroxychloroquine sulfate (2.5-20 mg/mL) reduces the rate of insulin degradation in liver homogenates isolated from non-diabetic and diabetic rats. Formulations containing Hydroxychloroquine have been used in the study of malaria, rheumatoid arthritis, and systemic lupus erythematosus.
    (S)-Hydroxychloroquine sulfate
  • HY-172572
    15(R),19(R)-Hydroxy prostaglandin E1
    15(R),19(R)-Hydroxy prostaglandin E1 is a dihydroxy metabolite/stereoisomer of Prostaglandin E1 (HY-B0131). 15(R),19(R)-Hydroxy prostaglandin E1 is found in the semen of some mammals, especially primates.
    15(R),19(R)-Hydroxy prostaglandin E1
  • HY-141176C
    cis-Cyclooctene-amine hydrochloride
    cis-Cyclooctene-amine hydrochloride is the cis isomer of TCO-amine hydrochloride (HY-141176A). TCO-amine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-amine hydrochloride is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    cis-Cyclooctene-amine hydrochloride
  • HY-100603B
    (R)-GSK-F1
    (R)-GSK-F1 is the R-type isomer of GSK-F1 (HY-100603). GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research.
    (R)-GSK-F1
  • HY-Z5058A
    (3S,5S)-Fluvastatin sodium
    (3S,5S)-Fluvastatin sodium is the isomer of Fluvastatin sodium (HY-14664A). Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor.
    (3S,5S)-Fluvastatin sodium
  • HY-179553
    (E)-ML233
    (E)-ML233 is the E isomer of ML233 (HY-125976). ML233 is a potent APJ agonist.
    (E)-ML233
  • HY-N13470
    meso-Astaxanthin
    meso-Astaxanthin is a natural stereoisomer of Astaxanthin (HY-B2163) with antioxidant activity and is found in a variety of aquatic animals. meso-Astaxanthin binds to human serum albumin in a monomeric form at a stoichiometric ratio; at low ligand-to-protein ratios, human serum albumin acts as a chiral template for supramolecular assembly at higher ratios. meso-Astaxanthin directly scavenges superoxide anions. meso-Astaxanthin can be used in the research of myocardial ischemia-reperfusion injury.
    meso-Astaxanthin
  • HY-Y1010S
    Oxiran-2-ylmethanol-d5
    Oxiran-2-ylmethanol-d5 is the deuterium labeled Oxiran-2-ylmethanol (Glycidol) (HY-Y1010). Oxiran-2-ylmethanol is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research.
    Oxiran-2-ylmethanol-d<sub>5</sub>
  • HY-154809
    (R)-M3913
    		99.17%
    (compound C-155) is a enantiomer of M3913. M3913 (HY-153359) is an antitumor compound. M3913 has antiproliferation activity against cancer cells.
    (R)-M3913
  • HY-76200C
    (R,R)-Voriconazole
    (R,R)-Voriconazole ((R,R)-UK-109496) is an enantiomer of Voriconazole (HY-76200). Voriconazole (UK-109496) is a second-generation broad-spectrum triazole antifungal compound that inhibits the biosynthesis of fungal ergosterol. Voriconazole exerts its antifungal activity by inhibiting the 14-α-lanosterol demethylation mediated by fungal cytochrome P450 enzymes. Voriconazole exhibits blood-brain barrier permeability.
    (R,R)-Voriconazole
  • HY-100540CR
    Golgicide A-1 (Standard)
    		Control
    Golgicide A-1 (Standard) is the analytical standard of Golgicide A-1 (HY-100540C). This product is intended for research and analytical applications. Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction.
    Golgicide A-1 (Standard)
  • HY-W614112
    (-)-Chloroquine
    (-)-Chloroquine is a chloroquine enantiomer.
    (-)-Chloroquine
  • HY-Z3151
    3'-(2-Fluorophenyl) ezetimibe
    		Control
    3'-(2-Fluorophenyl) ezetimibe is an isomer of the cholesterol transport inhibitor Ezetimibe (HY-17376).
    3'-(2-Fluorophenyl) ezetimibe
  • HY-167642
    (Z)-Rilpivirine
    (Z)-Rilpivirine ((Z)-R278474) is the (Z)-isomer of Rilpivirine (HY-10574). Rilpivirine is an effective and selective diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). It exhibits potent antiviral activity against both wild-type HIV (EC50 = 0.4 nM) and mutant strains (EC50 = 0.1-2.0 nM).
    (Z)-Rilpivirine
  • HY-178479A
    (Rac)-IDO1-IN-30
    (Rac)-IDO1-IN-30 is the Rac isomer of IDO1-IN-30 (HY-178479). IDO1-IN-30 is a potent and highly selective IDO1 inhibitor. IDO1-IN-30 has an IC50 of 4.8 nM to IDO1 in SKOV3 cells. IDO1-IN-30 does not show significant cytotoxicity at 25 µM in HepG2 cells. IDO1-IN-30 can eliminate inhibition of CYP450 enzymes (such as 3A4, 2C9, 2D6). IDO1-IN-30 can be used for research on cancer and inflammatory conditions.
    (Rac)-IDO1-IN-30
  • HY-163103
    (S)-Isomyosmine
    (S)-Isomyosmine is the S-enantiomer of Isomyosmine (HY-W701069). Isomyosmine is a nitrate reductase inhibitor. Isomyosmine is a nicotine related alkaloid present in solanecea plants containing nicotine. Isomyosmine can be used for research of inflammation and age-related disorders.
    (S)-Isomyosmine
  • HY-172049
    5-Fluoro PB-22 7-hydroxyisoquinoline isomer
    5-Fluoro PB-22 7-hydroxyisoquinoline isomer is a structural isomer of 5-Fluoro PB-22.
    5-Fluoro PB-22 7-hydroxyisoquinoline isomer