Oxiran-2-ylmethanol-d5
Based on 1 Customer Validation
Oxiran-2-ylmethanol-d5 is the deuterium labeled Oxiran-2-ylmethanol (Glycidol) (HY-Y1010). Oxiran-2-ylmethanol is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 1246819-20-4
- Formula: C3HD5O2
- Molecular Weight:79.11
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 1246819-20-4
-
Unlabeled Cas 556-52-5
-
Molecular Weight 79.11
-
Formula C3HD5O2
-
SMILES
OC([2H])([2H])C1([2H])C([2H])([2H])O1
-
Synonyms
Glycidol-d5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ikeda N, et al. Genotoxicity studies of glycidol fatty acid ester (glycidol linoleate) and glycidol. Food Chem Toxicol. 2012;50(11):3927-3933. [Content Brief]
[2]. Stichler S, et al. Thiol-ene Clickable Poly(glycidol) Hydrogels for Biofabrication. Ann Biomed Eng. 2017;45(1):273-285. [Content Brief]
[3]. Aasa J, et al. Internal Doses of Glycidol in Children and Estimation of Associated Cancer Risk. Toxics. 2019;7(1):7. Published 2019 Feb 1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)