2. Signaling Pathways
  3. Others
  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (434):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N16621
    Acetyldihydromicromelin B
    Acetyldihydromicromelin B is an isomer of Acetyldihydromicromelin A (HY-N2811). Acetyldihydromicromelin A is a coumarin.
    Acetyldihydromicromelin B
  • HY-186162A
    (R)-Betulinic acid-OBn
    (R)-Betulinic acid-OBn is an isomer of Betulinic acid-OBn(HY-186162).
    (R)-Betulinic acid-OBn
  • HY-W740803
    15-cis-Phytofluene
    15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis.
    15-cis-Phytofluene
  • HY-137862A
    (Rac)-1-Oleoyl lysophosphatidic acid
    (Rac)-1-Oleoyl lysophosphatidic acid is an isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid that can activate the LPA receptors .
    (Rac)-1-Oleoyl lysophosphatidic acid
  • HY-19489S3
    (±)-Levomepromazine-d3
    (±)-Levomepromazine-d3 ((±)-Methotrimeprazine-d3) is the deuterium labeled (±)-Levomepromazine (HY-19489). (±)-Levomepromazine ((±)-Methotrimeprazine) is the racemate of Levomepromazine (HY-B1693).
    (±)-Levomepromazine-d<sub>3</sub>
  • HY-W725194
    4-Fluoro deschloroketamine hydrochloride
    4-Fluoro deschloroketamine (4-FDCK) hydrochloride (Page 145) is an amine cyclohexane compound, with its (R)-configuration being Blixeprodil (HY-172419) (an NMDA receptor antagonist). 4-Fluoro deschloroketamine hydrochloride can be used for the study of depression.
    4-Fluoro deschloroketamine hydrochloride
  • HY-U00363A
    (rac)-CHEMBL333994
    (rac)-CHEMBL333994 is the racemate of CHEMBL333994 (HY-U00363). CHEMBL333994 is a potent and orally active Cholecystokinin A receptor (CCK-A receptor) antagonist, with an IC50 of 0.67 nM. CHEMBL333994 selectively antagonizes peripheral CCK receptors. CHEMBL333994 increases CCK mRNA level. CHEMBL333994 can be used for research of chronic pancreatitis.
    (rac)-CHEMBL333994
  • HY-19599A
    (Rac)-Vorozole
    (Rac)-Vorozole ((Rac)-R83842) is a racemate of Vorozole. Vorozole (HY-19599) is a potent and selective, orally active non-steroidal aromatase inhibitor.
    (Rac)-Vorozole
  • HY-123066A
    (E)-DIDS monohydrate sodium
    (E)-DIDS monohydrate sodium is the E-isomer of DIDS monohydrate sodium (HY-123066). DIDS is a hRAD51 inhibitor with an IC50 value of 90 μM. DIDS exhibits significant inhibitory activity against HIV-1 integrase with an IC50 value of 5 μM.
    (E)-DIDS monohydrate sodium
  • HY-128543
    Zidapamide
    Zidapamide (Compound 4a) is an isomer of indapamide (HY-B0259). Zidapamide has diuretic and natriuretic activities. Zidapamide is used in the study of hypertension.
    Zidapamide
  • HY-N18387
    trans-Psoralenoside
    trans-Psoralenoside is the trans isomer of Psoralenoside (HY-N7503). trans-Psoralenoside is present in the aerial parts of Ficus palmata. trans-Psoralenoside can be used in studies of liver diseases, kidney diseases and peptic ulcers.
    trans-Psoralenoside
  • HY-164575C
    (S)-NH2-NODAGA hydrochloride
    		99.91%
    (S)-NH2-NODAGA hydrochloride is the S isomer of NH2-NODAGA hydrochloride (HY-164575B). NH2-NODAGA hydrochloride is a NODAGA-type metal chelator that can bind to radioactive nuclides to prepare nuclide conjugates (RDC). NH2-NODAGA hydrochloride can react with diethyl fumarate in 0.5M phosphoric acid buffer to obtain NODAGA.SA. NODAGA.SA can target L-lysine urea-L-glutamic acid (KuE), and KuE is a key structure of prostate-specific membrane antigen (PSMA). NODAGA.SA.KuE can bind [68]Ga and can be used for PET examination in NMRInu/nu nude mice carrying LNCaP tumors.
    (S)-NH2-NODAGA hydrochloride
  • HY-N15890
    Tauroisolithocholanoic acid （sodium)
    Tauroisolithocholanoic acid sodium is an isomer of the naturally occurring Taurolithocholic acid (HY-113308).
    Tauroisolithocholanoic acid （sodium)
  • HY-50698A
    (S)-BI 2536
    (S)-BI 2536 (Compound 39g) is the enantiomer of BI 2536 (HY-50698). (S)-BI 2536 acts as an inhibitor of the BRD4 bromodomain and PLK1 kinase, with a Ki value of 54 nM against BRD4 and a Ki value of 0.42 nM against PLK1 kinase. (S)-BI 2536 exhibits anticancer activity against acute myeloid leukemia. (S)-BI 2536 can be used for the research of acute myeloid leukemia.
    (S)-BI 2536
  • HY-N8744A
    (+)-Vestitol
    (+)-Vestitol ((3S)-Vestitol) is an enantiomer of Vestitol (HY-N8744). Vestitol is the compound isolated from leaves of Trifolium arvense.
    (+)-Vestitol
  • HY-121582
    (E)-SI-2
    (E)-SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer.
    (E)-SI-2
  • HY-152859A
    Brigimadlin enantiomer
    		99.51%
    Brigimadlin (BI 907828) enantiomer is the Brigimadlin (HY-152859) enantiomer. Brigimadlin is an MDM2 inhibitor with anti-cancer activity.
    Brigimadlin enantiomer
  • HY-125784B
    (S)-Viloxazine hydrochloride
    		99.90%
    (S)-Viloxazine hydrochloride is the isomer of Viloxazine hydrochloride (HY-125784). Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist，EC50 for 5-HT2C b> is 32 μM，and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research.
    (S)-Viloxazine hydrochloride
  • HY-115907A
    (rac)-K20
    (rac)-K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity.
    (rac)-K20
  • HY-117799C
    (±)-LY-426965 dihydrochloride
    		Control
    (±)-LY-426965 dihydrochloride is a racemate of LY-426965 (HY-117799). LY426965 is a potent 5-HT1A receptor antagonist.
    (±)-LY-426965 dihydrochloride