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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D1391
    PbS/CdS QDs
    PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window.
    PbS/CdS QDs
  • HY-D2929
    BG-JF585
    		99.72%
    BG-JF585 is Benzylguanine-conjugated JF585 (HY-131025). Benzylguanine is the substrate for SNAP tags. JF585 is a fluorophore (λabs: 593 nm; λem: 611 nm).
    BG-JF585
  • HY-D1432
    FITC-C6-DEVD-FMK
    FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor.
    FITC-C6-DEVD-FMK
  • HY-W248118
    Pyrromethene 556
    		99.03%
    Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 556
  • HY-D1802
    Vari Fluor 425 SE
    Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 425 SE
  • HY-D2282
    DFHBI-BI
    		99.12%
    DFHBI-BI is a mimic of the green fluorescence protein chromophore. DFHBI-BI can be bound and activated by Broccoli ( a fluorogenic RNA aptamer) with higher affinity. DFHBI-BI prevents thermal unfolding of Broccoli at 37°C in mammalian cells, subsequently forming more fluorescent Broccoli-BI complexes. The fluorescence wavelength is 559/635 nm.
    DFHBI-BI
  • HY-P6027A
    H-D-CHA-Ala-Arg-pNA diacetate
    		99.83%
    H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay.
    H-D-CHA-Ala-Arg-pNA diacetate
  • HY-D1071
    DBCO-PEG12-TCO
    DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    DBCO-PEG12-TCO
  • HY-D2312
    Mito-Rh-S
    Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC).
    Mito-Rh-S
  • HY-W142117
    H-Asp(AMC)-OH
    		99.75%
    H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM.
    H-Asp(AMC)-OH
  • HY-D1438
    RH 414
    RH 414 is the styryl pyridinium dye. RH 414 can be used for optical monitoring of synaptic vesicle membrane trafficking.
    RH 414
  • HY-D1180
    DTTCI
    DTTCI (3,3′-Diethylthiatricarbocyanine iodide) is an infrared photographic sensitizing dye. DTTCI is a highly sensitive chiroptical reporter of DNA helicity and sequence.
    DTTCI
  • HY-D1747
    Rhodamine 3B perchlorate
    		98.60%
    Rhodamine 3B perchlorate is a laser dye,
    Rhodamine 3B perchlorate
  • HY-D0159A
    ZnAF-1F tetraTFA
    		99.35%
    ZnAF-1F tetraTFA is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm.
    ZnAF-1F tetraTFA
  • HY-D1072
    DiOC5(3)
    		99.64%
    DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical.
    DiOC5(3)
  • HY-D1963
    ATTO 565 streptavidin
    ATTO 565 Streptavidin is a streptavidin derivative of ATTO 565, it can label protein or antibody, the maximum excitation/emission wavelength: 564/590 nm.
    ATTO 565 streptavidin
  • HY-W250928D
    Biotin-PEG3400-azide
    		99.13%
    Biotin-PEG3400-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG3400-azide
  • HY-D2708
    Cy3 Dextran (MW 10000)
    Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm).
    Cy3 Dextran (MW 10000)
  • HY-D2001A
    ATTO 488 NHS ester TEA
    TTO 488 NHS ester TEA is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. TTO 488 NHS ester TEA is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
    ATTO 488 NHS ester TEA
  • HY-D0039
    3-Cyanoumbelliferone
    		≥98.0%
    3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM.
    3-Cyanoumbelliferone
Cat. No. Product Name / Synonyms Application Reactivity