3-Cyanoumbelliferone
Based on 1 Customer Validation
3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 19088-73-4
- Formula: C10H5NO3
- Molecular Weight:187.15
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Ki: 2.9 μM (MIF)[1]
Chemical Information
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CAS No. 19088-73-4
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Appearance Solid
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Molecular Weight 187.15
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Formula C10H5NO3
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Color Yellow to orange
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SMILES
N#CC1=CC2=CC=C(O)C=C2OC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 6.67 mg/mL (35.64 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3433 mL | 26.7165 mL | 53.4331 mL | 133.5827 mL |
| 5 mM | 1.0687 mL | 5.3433 mL | 10.6866 mL | 26.7165 mL | |
| 10 mM | 0.5343 mL | 2.6717 mL | 5.3433 mL | 13.3583 mL | |
| 15 mM | 0.3562 mL | 1.7811 mL | 3.5622 mL | 8.9055 mL | |
| 20 mM | 0.2672 mL | 1.3358 mL | 2.6717 mL | 6.6791 mL | |
| 25 mM | 0.2137 mL | 1.0687 mL | 2.1373 mL | 5.3433 mL | |
| 30 mM | 0.1781 mL | 0.8906 mL | 1.7811 mL | 4.4528 mL |