ZnAF-1F tetraTFA
Based on 1 Customer Validation
ZnAF-1F tetraTFA is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm.
For research use only. We do not sell to patients.
- Purity: 99.35%
- Formula: C42H30F14N4O13
- Molecular Weight:1064.68
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
ZnAF-1F tetraTFA (1 μM) shows an Kon value of 3.5 x 106 M-1s-1, and an Koff value of 7.7 x 10-3 s-1 in 100 mM HEPES buffer[1].
ZnAF-1F tetraTFA is a Zn sensors in neutral and slightly acidic conditions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1064.68
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Formula C42H30F14N4O13
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Color Brown to black
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SMILES
O=C1OC2(C3=C(OC4=C2C=C(F)C(O)=C4)C=C(O)C(F)=C3)C5=C1C=C(NCCN(CC6=NC=CC=C6)CC7=NC=CC=C7)C=C5.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Hirano T, et al. Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc. 2002 Jun 12;124(23):6555-62. [Content Brief]
[2]. Zhaohua Dai, et al. Tailoring tripodal ligands for zinc sensing. New J. Chem., 2007,31, 1708-1718.
[3]. Que EL, et al. Metals in neurobiology: probing their chemistry and biology with molecular imaging. Chem Rev. 2008 May;108(5):1517-49. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)