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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W724298
    Hexadecyltrimethylammonium chloride-d33
    N,N,N-Trimethylhexadecan-1-aminium-d33 chloride is the deuterium labeled Hexadecyltrimethylammonium chloride (HY-W011291). Hexadecyltrimethylammonium chloride is a biochemical assay reagent.
    Hexadecyltrimethylammonium chloride-d<sub>33</sub>
  • HY-146938S
    CER11-2’R-d9
    99.0%
    CER11-2’R-d9 is deuterium labeled CER11-2’R.
    CER11-2’R-d<sub>9</sub>
  • HY-N0086S3
    N6-Methyladenosine-13C3
    N6-Methyladenosine-13C3 (6-Methyladenosine-13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
    N6-Methyladenosine-<sup>13</sup>C<sub>3</sub>
  • HY-13599S4
    Cladribine-13C,15N2
    Cladribine-13C,15N2 (2-Chloro-2′-deoxyadenosine-13C,15N2) is the 13C- and 15N-labeled Cladribine (HY-13599). Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active?adenosine deaminase?inhibitor. Cladribine functions as an inhibitor of?DNA synthesis?to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis.
    Cladribine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-W766163
    7-Hydroxy coumarin glucuronide-d5 sodium
    7-Hydroxy coumarin glucuronide-d5 sodium is the deuterium labeled 7-Hydroxy coumarin glucuronide sodium (HY-120201). 7-Hydroxy coumarin glucuronide sodium is a benzopyrone and a metabolite of 7-hydroxy coumarin.
    7-Hydroxy coumarin glucuronide-d<sub>5</sub> sodium
  • HY-W015427S
    1,2-Dichloro-3-methylbenzene-d3
    98.7%
    1,2-Dichloro-3-methylbenzene-d3 is the deuterium labeled 1,2-Dichloro-3-methylbenzene.
    1,2-Dichloro-3-methylbenzene-d<sub>3</sub>
  • HY-W750464
    Catharanthine-d3 Tartrate Salt
    Catharanthine-d3 Tartrate Salt is the deuterium labeled Catharanthine Tartrate Salt.
    Catharanthine-d<sub>3</sub> Tartrate Salt
  • HY-W145652S1
    D-Altrose-2-13C
    D-Altrose-2-13C is the 13C labeled D(+)-Altrose[1].
    D-Altrose-2-<sup>13</sup>C
  • HY-W703574
    2,5-Dimethoxy-4-methylbenzaldehyde-d6
    2,5-Dimethoxy-4-methylbenzaldehyde-d6 is the deuterium labeled 2,5-Dimethoxy-4-methylbenzaldehyde (HY-W100882).
    2,5-Dimethoxy-4-methylbenzaldehyde-d<sub>6</sub>
  • HY-10572BS1
    (Rac)-Efavirenz-d5
    (Rac)-Efavirenz-d5 is deuterium labeled (Rac)-Efavirenz. (Rac)-Efavirenz-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (Rac)-Efavirenz-d<sub>5</sub>
  • HY-B0637S1
    Bezafibrate-d4
    Bezafibrate-d4 is deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.
    Bezafibrate-d<sub>4</sub>
  • HY-B1490AS1
    Imipramine-d4
    Imipramine-d4 is deuterium labeled Imipramine. Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects.
    Imipramine-d<sub>4</sub>
  • HY-113410S
    3-Methylglutaric acid-d4
    3-Methylglutaric acid-d4 is the deuterium labeled 3-Methylglutaric acid (HY-113410). 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration.
    3-Methylglutaric acid-d<sub>4</sub>
  • HY-109582S
    ADT-OH-d4
    ADT-OH-d4 (ACS 1-d4) is the deuterium labeled ADT-OH (HY-109582). ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases.
    ADT-OH-d<sub>4</sub>
  • HY-150985S
    2,2'-Dichloro bisphenol a mono-D-glucuronide-d12
    2,2'-Dichloro bisphenol a mono-D-glucuronide-d12 is the deuterium labeled 2,2'-Dichloro bisphenol a mono-D-glucuronide.
    2,2'-Dichloro bisphenol a mono-D-glucuronide-d<sub>12</sub>
  • HY-14740S
    Elvitegravir-d8
    Elvitegravir-d8 is deuterium labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
    Elvitegravir-d<sub>8</sub>
  • HY-B0535AS
    Ethambutol-d4 dihydrochloride
    Ethambutol-d4 dihydrochloride is deuterated labeled Ethambutol dihydrochloride (HY-B0535A). Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.
    Ethambutol-d<sub>4</sub> dihydrochloride
  • HY-15592S2
    Cabotegravir-d3-1
    Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research
    Cabotegravir-d<sub>3</sub>-1
  • HY-W725613
    Diethylamino hydroxybenzoyl hexyl benzoate-d4
    Diethylamino hydroxybenzoyl hexyl benzoate-d4 is the deuterium labeled Diethylamino hydroxybenzoyl hexyl benzoate (HY-109656). Diethylamino hydroxybenzoyl hexyl benzoate is a photostable UV-A absorber.
    Diethylamino hydroxybenzoyl hexyl benzoate-d<sub>4</sub>
  • HY-15321S1
    Etoricoxib-13C,d3
    Etoricoxib-13C,d3 is the 13C- and deuterium labeled Etoricoxib. Etoricoxib (MK-0663) is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.
    Etoricoxib-<sup>13</sup>C,d<sub>3</sub>