N6-Methyladenosine-13C3
N6-Methyladenosine-13C3 (6-Methyladenosine-13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
For research use only. We do not sell to patients.
- Formula: C813C3H15N5O4
- Molecular Weight:284.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1867-73-8
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Molecular Weight 284.25
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Formula C813C3H15N5O4
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SMILES
O[C@H]1[C@@H](O)[C@H](N2[13CH]=NC3=C2N=[13CH]N=C3N[13CH3])O[C@@H]1CO
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Synonyms
6-Methyladenosine-13C3; N-Methyladenosine-13C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. [Content Brief]
[2]. Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21(8):1511-8. [Content Brief]
[3]. Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)