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  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds 関連製品 (10876):

製品番号 製品名 製品効果 純度 構造式
  • HY-W759997
    Reproterol-d3
    Reproterol-d3 is the deuterium labeled Reproterol (HY-135490). Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research.
    Reproterol-d<sub>3</sub>
  • HY-23430S
    TES-d15
    TES-d15 is the deuterium labeled TES (HY-23430). TES is an excellent hydrogen ion buffer. TES has characteristics such as an appropriate dissociation constant, a low metal-binding constant, and high water solubility. TES can be used in the research of mammalian cell culture, viruses, and so on.
    TES-d<sub>15</sub>
  • HY-133115S
    N-Desmethylnefopam-d5
    N-Desmethylnefopam-d5 is the deuterium labeled N-Desmethylnefopam (HY-133115). N-Desmethylnefopam is the main metabolite of Nefopam. N-Desmethylnefopam is a centrally-acting but non-opioid analgesic agent, for the relief of moderate to severe pain. Nefopam targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo.
    N-Desmethylnefopam-d<sub>5</sub>
  • HY-14649S5
    Retinoic acid-d3
    Retinoic acid-d3 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid-d<sub>3</sub>
  • HY-W013973S
    p-Terphenyl-d14 99.8%
    p-Terphenyl-d14 is the deuterium labeled p-Terphenyl (HY-W013973). p-Terphenyl is a specialty material, and may be used in ionized radiation detectors, nonpolar laser dye, and single molecule optical probe of scanning near-field microscopy. p-Terphenyl can be used to synthesis p-Terphenyl derivatives, for the research of cancer and inflammatory diseases.
    p-Terphenyl-d<sub>14</sub>
  • HY-W748285
    2-Octanamidoacetic acid-13C2,15N
    2-Octanamidoacetic acid-13C2,15N (N-octanoylglycine-13C2,15N) is the 13C- and 15N-labeled 2-Octanamidoacetic acid (HY-W099646).
    2-Octanamidoacetic acid-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W048482S
    rU Phosphoramidite-13C2,d1
    rU Phosphoramidite-13C2,d1 (DMT-2'O-TBDMS-rU phosphoramidite-13C2,d1) is deuterium and 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
    rU Phosphoramidite-<sup>13</sup>C<sub>2</sub>,d<sub>1</sub>
  • HY-10260S1
    Vandetanib-d4
    Vandetanib-d4 is the deuterium labeled Vandetanib. Vandetanib (ZD6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).
    Vandetanib-d<sub>4</sub>
  • HY-W014589S
    2,4-Di-tert-butylphenol-d19
    2,4-Di-tert-butylphenol-d19 (2,4-DTBP-d19) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances.
    2,4-Di-tert-butylphenol-d<sub>19</sub>
  • HY-18102BS
    GLPG0492-13C,d3 racemate
    GLPG0492-13C,d3 racemate is 13C-labeled GLPG0492 (racemate) (HY-18102B). GLPG0492 racemate is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 racemate exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 racemate effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 racemate prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy.
    GLPG0492-<sup>13</sup>C,d<sub>3</sub> racemate
  • HY-W015824S2
    DL-Aspartic acid-3-13C
    DL-Aspartic acid-3-13C is the 13C labeled DL-Aspartic acid.
    DL-Aspartic acid-3-<sup>13</sup>C
  • HY-W740127
    Quinidine-d3 N-Oxide
    Quinidine-d3 N-Oxide is the deuterium labeled Quinidine N-Oxide.
    Quinidine-d<sub>3</sub> N-Oxide
  • HY-N0537S13
    Xylose-d-4
    Xylose-d-4 is the deuterium labeled Xylose.
    Xylose-d-4
  • HY-143780S
    Oseltamivir-d5 (hydrochloride)
    Oseltamivir-d5 (hydrochloride) is the deuterium labeled Oseltamivir hydrochloride.
    Oseltamivir-d<sub>5</sub> (hydrochloride)
  • HY-W741177
    2-(Benzylamino)-2-phenylbutan-1-ol-d5
    2-(Benzylamino)-2-phenylbutan-1-ol-d5 is the deuterium labeled 2-(Benzylamino)-2-phenylbutan-1-ol (HY-W702028).
    2-(Benzylamino)-2-phenylbutan-1-ol-d<sub>5</sub>
  • HY-W013059S2
    DMT-dA(bz) Phosphoramidite-d9
    DMT-dA(bz) Phosphoramidite-d9 (DA-CE phosphoramidite-d9) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.
    DMT-dA(bz) Phosphoramidite-d<sub>9</sub>
  • HY-W718786
    Etofenprox-phenol-d5
    Etofenprox-phenol-d5 is the deuterium labeled Etofenprox (HY-B0816). Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research.
    Etofenprox-phenol-d<sub>5</sub>
  • HY-B0400AS1
    L-Sorbitol-13C-1
    L-Sorbitol-13C-1 is the 13C labeled L-Sorbitol.
    L-Sorbitol-<sup>13</sup>C-1
  • HY-W010708S2
    Cholesteryl palmitate-d31
    Cholesteryl palmitate-d31 is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).
    Cholesteryl palmitate-d<sub>31</sub>
  • HY-165700S
    Iodosulfuron methyl ester-d3
    Iodosulfuron methyl ester-d3 is deuterium labeled Iodosulfuron methyl ester.
    Iodosulfuron methyl ester-d<sub>3</sub>