Etofenprox-phenol-d5
Etofenprox-phenol-d5 is the deuterium labeled Etofenprox (HY-B0816). Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research.
For research use only. We do not sell to patients.
- CAS No.: 2733270-19-2
- Formula: C25H23D5O3
- Molecular Weight:381.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2733270-19-2
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Unlabeled Cas 80844-07-1
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Molecular Weight 381.52
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Formula C25H23D5O3
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SMILES
[2H]C1=C(OC2=CC(COCC(C)(C)C3=CC=C(C=C3)OCC)=CC=C2)C([2H])=C(C([2H])=C1[2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hemingway J. Efficacy of etofenprox against insecticide susceptible and resistant mosquito strains containing characterized resistance mechanisms. Med Vet Entomol. 1995 Oct;9(4). [Content Brief]
[2]. Hojo Y, et al. Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action. J Toxicol Sci. 2012;37(2):297-306. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)