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Etofenprox 

Cat. No.: HY-B0816 Purity: 98.49%
COA Handling Instructions

Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research.

For research use only. We do not sell to patients.

Etofenprox Chemical Structure

Etofenprox Chemical Structure

CAS No. : 80844-07-1

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research[1][2].

In Vitro

Etofenprox induces toxicity in the housefly M. domestica with LD50 of 23 ng/fly)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Etofenprox (powder; 0.25, 0.5, and 1%; p.o.; daily for 8 wk) shows a promotion on liver tumor in male F344 rats, indicating the activation of constitutive active/androstane receptor (CAR) and enhances microsomal ROS production, resulting in the up-regulation of Nrf2 gene batteries[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

376.49

Appearance

Solid

Formula

C25H28O3

CAS No.
SMILES

CC(C)(C1=CC=C(OCC)C=C1)COCC2=CC=CC(OC3=CC=CC=C3)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (265.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6561 mL 13.2806 mL 26.5611 mL
5 mM 0.5312 mL 2.6561 mL 5.3122 mL
10 mM 0.2656 mL 1.3281 mL 2.6561 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (6.64 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: 2.5 mg/mL (6.64 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (6.64 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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Etofenprox Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Etofenprox
Cat. No.:
HY-B0816
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