Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Verwandte Produkte (10876):

Art. -Nr.	Produktname	Wirkung	Reinheit	Chemical Structure

HY-13632S6

Exemestane-d₄
Exemestane-d₄ (FCE 24304-d₄) is deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research.

HY-W749498

Metrafenone-d₉
Metrafenone-d₉ is deuterium labeled Metrafenone.

HY-32709S

Telcagepant-d₈
Telcagepant-d₈ (MK-0974-d₈) is deuterium labeled Telcagepant. Telcagepant (MK-0974) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with K_is of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively.

HY-W748705

Aminomethanephosphonic acid-¹³C,¹⁵N
Aminomethanephosphonic acid-¹³C,¹⁵N is ¹³C and ¹⁵N labeled (((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phosphonic acid.

HY-W709166

2-(Ethyl)-3,5-dimethylpyrazine-d₅
2-(Ethyl-d₅)-3,5-dimethylpyrazine is deuterated labeled 2-(Ethyl)-3,5-dimethylpyrazine.

HY-132355S

(E)-Fluvoxamine-d₃ maleate
(E)-Fluvoxamine-d₃ (maleate) is the deuterium labeled (E)-Fluvoxamine maleate.

HY-A0088S

Cefotaxime-d₃ sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.

HY-W654175

Duloxetine-d₇ maleate
Duloxetine-d₇ (maleate) is deuterium labeled Duloxetine Maleate.

HY-14740S2

Elvitegravir-¹³C₆
Elvitegravir-¹³C₆ (GS-9137-¹³C₆) is ¹³C labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1_IIIB, HIV-2_EHO and HIV-2_ROD with IC₅₀ of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

HY-B0084S3

Dienogest-¹³C₂,¹⁵N
Dienogest-¹³C₂,¹⁵N (STS 557-¹³C₂,¹⁵N) is ¹³C- and ¹⁵N-labeled Dienogest (HY-B0084).

HY-N1393S

2-Methoxybenzoic acid-¹³C₆
2-Methoxybenzoic acid (NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether)-¹³C₆ is the ¹³C-labeled 2-Methoxybenzoic acid (HY-N1393). 2-Methoxybenzoic acid is a natural compound with potential salicylate-like effect. 2-Methoxybenzoic acid inhibits carbonic anhydrase activity, elevates intraplatelet cyclic guanosine monophosphate level, and suppresses cytosolic phospholipase A₂ phosphorylation. 2-Methoxybenzoic acid suppresses platelet reactivity, including decreased spreading, retraction, and aggregation in platelets. 2-Methoxybenzoic acid ameliorates arterial thrombosis in a dose-dependent manner without affecting normal hemostasis in mice. 2-Methoxybenzoic acid can be used for the research of arterial thrombosis.

HY-W188178S

2-[Methyl(nitroso)amino]acetic acid-d₃
2-[Methyl(nitroso)amino]acetic acid-d₃ is the deuterium labeled 2-[methyl(nitroso)amino]acetic acid.

HY-W705479

Pazopanib-d₃ hydrochloride
Pazopanib-d₃ (hydrochloride) (GW786034-d₃ (hydrochloride)) is deuterium labeled Pazopanib (Hydrochloride). Pazopanib Hydrochloride (GW786034 Hydrochloride) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with an IC₅₀ of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.

HY-W705485

N-Methylmethan-d₃-amine hydrochloride
N-Methylmethan-d₃-amine (hydrochloride) is deuterium labeled N-Methylmethan-amine (hydrochloride).

HY-17007S2

Saquinavir-¹³C₆
Saquinavir-¹³C₆ (Ro 31-8959-¹³C₆) is ¹³C labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells.

HY-155912S

2-Allyl-3-methylpyrazine-d₃
2-Allyl-3-methylpyrazine-d₃ is deuterated labeled 2-Allyl-3-methylpyrazine.

HY-15409S1

Empagliflozin-¹³C₆
Empagliflozin-¹³C₆ (BI 10773-¹³C₆) is ¹³C labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC₅₀ of 3.1 nM for human SGLT-2.

HY-W715198S

4-Bromo-2,3,7,8-tetrachlorodibenzofuran-¹³C₁₂
4-Bromo-2,3,7,8-tetrachlorodibenzofuran-¹³C₁₂ is ¹³C labeled 4-Bromo-2,3,7,8-tetrachlorodibenzo[b,d]furan.

HY-W728761

Voxelotor-d₇
Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization.

HY-16774S2

Vericiguat-d₆
Vericiguat-d₆ (BAY1021189-d₆) is deuterium labeled Vericiguat. Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator.

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