Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W706234

Nonanoyl-CoA-d₁₇
Nonanoyl-CoA-d₁₇ (Pelargonoyl-CoA-d₁₇) is the deuterium labeled Nonanoyl-CoA (HY-E70246). Nonanoyl-CoA is a medium-chain fatty acyl-CoA that can be used as substrate for the medium-chain hydrolase.

HY-113168AS

(±)-Butyrylcarnitine-d₉
(±)-Butyrylcarnitine-d₉ is deuterium labeled (±)-Butyrylcarnitine.

HY-W343292S

2-Methylbutyl acetate-¹³C₂
2-Methylbutyl acetate-¹³C₂ is ¹³C labeled 2-Methylbutyl acetate.

HY-W010712S1

Fmoc-His(Trt)-OH-¹⁵N₃
Fmoc-His(Trt)-OH-¹⁵N₃ is the ¹⁵N labeled Fmoc-His(Trt)-OH (HY-W010712). Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation.

HY-17373S2

Posaconazole-d₃
Posaconazole-d₃ (SCH 56592-d₃) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

HY-10284S4

Linagliptin-d₅
Linagliptin-d₅ (BI 1356-d₅) is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC₅₀ of 1 nM.

HY-10121S4

Asenapine-d₃,¹³C
Asenapine-d₃,¹³C (Org 5222-d₃,¹³C) is deuterium and ¹³C labeled Asenapine. Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors (pK_i: 8.4-10.5), adrenoceptors (pK_i: 8.9-9.5), dopamine receptors (pK_i: 8.9-9.4) and histamine receptors (pK_i: 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder.

HY-143684S

N-(3-Mercapto-2-methylpropanoyl)glycine-d₅
N-(3-Mercapto-2-methylpropanoyl)glycine-d₅ is the deuterium labeled N-(3-Mercapto-2-methylpropanoyl)glycine.

HY-18342S1

Diflunisal-¹³C₆
Diflunisal-¹³C₆ (MK-647-¹³C₆) is ¹³C labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-14397S2

Indometacin-d₇
Indometacin-d₇ is deuterated labeled Indomethacin (HY-14397). Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC₅₀ values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research.

HY-106254S1

Vapendavir-d₆
Vapendavir-d₆ (BTA798-d₆) is deuterium-labeled Vapendavir (HY-106254).

HY-W727768

Salicylic acid 2-O-β-D-glucoside-d₄
Salicylic acid 2-O-β-D-glucoside-d₄ is deuterium labeled Salicylic acid 2-O-β-D-glucoside.

HY-132508S

Etravirine-d₈
Etravirine-d₈ is the deuterium labeled Etravirine. Etravirine (R165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

HY-W755036

Oxytetracycline-¹³C,d₃ hydrochloride
Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity.

HY-B0411S2

Domperidone-₁₃C₆
Domperidone-¹³C₆ (R33812-¹³C₆) is ¹³C labeled Domperidone. Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine.

HY-14291S5

Vildagliptin-d₆
Vildagliptin-d₆ (LAF237-d₆ ) is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.

HY-N2325S

D-(+)-Cellobiose-¹³C
D-(+)-Cellobiose-¹³C is the ¹³C labeled D-(+)-Cellobiose. D-(+)-Cellobiose is an endogenous metabolite.

HY-146876S

C18:0 GM1 Ganglioside-d₅ ammonium		99.0%
C18:0 GM1 Ganglioside-d₅ (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).

HY-16935S

Mavatrep-d₆
Mavatrep-d₆ (JNJ-39439335-d₆) is a deuterated labeled Mavatrep (HY-16935). Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (K_i=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca²⁺ influx with an IC₅₀ value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain.

HY-W718472S

3,3′-Dichloro biphenyl-¹³C₁₂
3,3′-Dichloro biphenyl-¹³C₁₂ is ¹³C labeled 3,3'-Dichloro-1,1'-biphenyl.

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