Fmoc-His(Trt)-OH-15N3
Fmoc-His(Trt)-OH-15N3 is the 15N labeled Fmoc-His(Trt)-OH (HY-W010712). Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation.
For research use only. We do not sell to patients.
- CAS No.: 1217696-12-2
- Formula: C40H3315N3O4
- Molecular Weight:622.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217696-12-2
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Unlabeled Cas 109425-51-6
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Molecular Weight 622.69
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Formula C40H3315N3O4
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SMILES
O=C(O)[C@H](CC1=C[15N](C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=[15N]1)[15NH]C(OCC5C6=C(C7=C5C=CC=C7)C=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Aggarwal S, et al. [DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer. 2011 Oct 1;129(7):1611-23. [Content Brief]
[3]. Kamysz E, et al. Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum. J Pept Sci. 2013 Mar;19(3):166-72. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)