109425-51-6
Chemical Structure
Fmoc-His(Trt)-OH
- CAS No.: 109425-51-6
- Formula:C40H33N3O4
- Molecular Weight:619.71
IUPAC Name: Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-Nt-trityl-L-histidine
InChIKey: XXMYDXUIZKNHDT-QNGWXLTQSA-N
SMILES: O=C([C@@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC4=CN(C=N4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)O
Biological Activity: Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH2 group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fmoc-His(Trt)-OH | 99.88% | Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH2 group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration. | ||||||||||||||||||||
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Fmoc-His(Trt)-OH-15N3 | Fmoc-His(Trt)-OH-15N3 is the 15N labeled Fmoc-His(Trt)-OH (HY-W010712). Fmoc-His (Trt)-OH is a histidine derivative. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation. | |||||||||||||||||||||
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