1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mAChR
  4. mAChR4 Isoform
  5. mAChR4 Antagonist

mAChR4 Antagonist

mAChR4 Antagonists (5):

Cat. No. Product Name Effect Purity
  • HY-B0394
    Atropine sulfate monohydrate
    Antagonist 99.64%
    Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively.
  • HY-B0321
    Tropicamide
    Antagonist 99.30%
    Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist.
  • HY-107647
    (S)-(+)-Dimethindene maleate
    Antagonist ≥99.0%
    (S)-(+)-Dimethindene maleate, an enantiomer, is a potent M2-selective muscarinic receptor antagonist (pA2 = 7.86/7.74; pKi = 7.78).
  • HY-148527
    LAS190792
    Antagonist
    LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively.
  • HY-141711
    VU6028418
    Antagonist 99.52%
    VU6028418 is a potent, highly selective and orally bioavailable M4 mAChR antagonist with an IC50 of 4.1 nM against hM4.